Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20045032 | 0.84 | POLB (0.49) | FFAR1FFAR4KEAP1CYP1A2CYP2D6 | |
| SCHEMBL15355980 | 0.84 | FFAR1 (0.52) | FFAR1FFAR4KEAP1CYP1A2CYP2D6 | |
| SCHEMBL27700801 | 0.83 | FFAR1 (0.50) | FFAR1FFAR4KEAP1RXRGRXRA | |
| SCHEMBL586063 | 0.82 | FFAR1 (0.58) | FFAR1FFAR4KEAP1 | |
| SCHEMBL30782466 | 0.79 | FFAR1 (0.55) | FFAR1FFAR4KEAP1 | |
| SCHEMBL16663706 | 0.79 | HTR2A (0.45) | FFAR1 | |
| SCHEMBL3336184 | 0.79 | FFAR1 (0.55) | FFAR1FFAR4KEAP1 | |
| SCHEMBL7522054 | 0.79 | CYP4F2 (0.59) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL28260992 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4KEAP1CYP1A2CYP2D6 | |
| SCHEMBL585740 | 0.77 | FFAR1 (0.55) | FFAR1FFAR4KEAP1RXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001020995-A9 | COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF | UNIV WASHINGTON (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2001020995-A1 | COMPOUNDS DIRECTED AGAINST PILUS BIOGENESIS AND ACTIVITY IN PATHOGENIC BACTERIA; METHODS AND COMPOSITIONS FOR SYNTHESIS THEREOF | WASHINGTON UNIVERSITY (US) | 2001-03-29 | — | — | WO | disclosed |