Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | PTEN | P60484 | 1/20 | 0.41 |
| ▸ | PTPMT1 | Q8WUK0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15355980 | 0.90 | FFAR1 (0.52) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL28261013 | 0.79 | NPSR1 (0.53) | FFAR1KEAP1FFAR4 | |
| SCHEMBL30159367 | 0.79 | NPSR1 (0.53) | FFAR1KEAP1FFAR4 | |
| SCHEMBL18541177 | 0.79 | PKM (0.51) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL20045032 | 0.79 | POLB (0.49) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL23495102 | 0.78 | FFAR1 (0.55) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL31307940 | 0.78 | FFAR1 (0.55) | FFAR1KEAP1CA1CA2FFAR4 | |
| SCHEMBL7581192 | 0.78 | FFAR1 (0.52) | FFAR1KEAP1FFAR4CYP1A2CYP2D6 | |
| SCHEMBL1750638 | 0.78 | FFAR1 (0.51) | FFAR1KEAP1FFAR4 | |
| SCHEMBL4928195 | 0.78 | EGFR (0.42) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829305-B | NRF2 regulator | 葛兰素史密斯克莱知识产权发展有限公司 | 2018-11-30 | — | — | CN | disclosed |