Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474139 | 1.00 | CRHR1 (0.89) | CRHR1LCK | |
| SCHEMBL16606730 | 0.94 | CRHR1 (1.00) | CRHR1LCK | |
| SCHEMBL27516758 | 0.82 | CRHR1 (0.71) | CRHR1LCK | |
| SCHEMBL7217257 | 0.79 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL7217253 | 0.79 | CRHR1 (0.54) | CRHR1 | |
| SCHEMBL5866990 | 0.77 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7472645 | 0.73 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL7472647 | 0.73 | CRHR1 (0.65) | CRHR1 | |
| SCHEMBL7504068 | 0.72 | CRHR1 (0.59) | CRHR1 | |
| SCHEMBL7626666 | 0.71 | CRHR1 (0.56) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0935601-A4 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARM CO (US) | 2002-08-07 | — | — | EP | claimed |
| EP-0935601-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | Du Pont Pharmaceuticals Company (US) | 1999-08-18 | — | — | EP | claimed |
| WO-1997035539-A2 | ARYLAMINO FUSED PYRIDINES AND PYRIMIDINES | DU PONT PHARMACEUTICALS COMPANY (US) | 1997-10-02 | — | — | WO | claimed |
| US-6448261-B1 | CORTICOTROPIN RELEASING FACTOR ANTAGONISTS; TREATING ANXIETY, DEPRESSION, AND OTHER PSYCHIATRIC AND NEUROLOGICAL DISORDERS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-09-10 | — | — | US | disclosed |
| US-6107300-A | CORTICOTROPIN RELEASING FACTOR ANTAGONIST; PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS (US) | 2000-08-22 | — | — | US | disclosed |