Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL758249 | 0.78 | MEN1 (0.32) | — | |
| SCHEMBL3070241 | 0.73 | CETP (0.33) | CETP | |
| SCHEMBL758196 | 0.69 | SLC6A4 (0.32) | — | |
| SCHEMBL6950343 | 0.67 | CA1 (0.41) | — | |
| SCHEMBL14297798 | 0.67 | TRPV1 (0.40) | EPAS1CETP | |
| SCHEMBL25237882 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL8848350 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL30390224 | 0.65 | PARP1 (0.33) | — | |
| SCHEMBL3709776 | 0.64 | PARP1 (0.36) | — | |
| SCHEMBL31191131 | 0.63 | PARP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954668-B9 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1954668-B1 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-28 | — | — | EP | disclosed |