Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6950343 | 0.75 | CA1 (0.41) | SLC6A4 | |
| SCHEMBL3070241 | 0.73 | CETP (0.33) | — | |
| SCHEMBL13491454 | 0.70 | KDM4E (0.43) | SLC6A4DUT | |
| SCHEMBL14033969 | 0.69 | CETP (0.47) | — | |
| SCHEMBL758195 | 0.69 | EPAS1 (0.31) | — | |
| SCHEMBL11720083 | 0.68 | MAOB (0.43) | SLC6A4 | |
| SCHEMBL16233093 | 0.68 | DUT (0.40) | SLC6A4DUT | |
| SCHEMBL17064738 | 0.67 | CETP (0.43) | — | |
| SCHEMBL31067601 | 0.67 | CETP (0.43) | — | |
| SCHEMBL25237882 | 0.67 | PARP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954668-B9 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1954668-B1 | HOMO- AND HETEROCYCLIC COMPOUNDS SUITABLE AS CETP INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-28 | — | — | EP | disclosed |