Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 11/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.60 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426120 | 0.94 | ITGB1 (0.55) | ITGA4ITGB1CTSA | |
| SCHEMBL7382674 | 0.94 | ITGB1 (0.64) | ITGA4ITGB1CTSAMEN1KMT2A | |
| SCHEMBL7384591 | 0.94 | ITGA4 (0.61) | ITGA4ITGB1CTSAMEN1KMT2A | |
| SCHEMBL7422603 | 0.91 | ITGA4 (0.51) | ITGA4ITGB1CTSAP2RX7 | |
| SCHEMBL7427785 | 0.90 | ITGA4 (0.59) | ITGA4ITGB1P2RX7MAPTMEN1 | |
| SCHEMBL7423658 | 0.90 | ITGB1 (0.65) | ITGA4ITGB1MEN1KMT2A | |
| SCHEMBL5700846 | 0.89 | ITGB1 (0.71) | ITGA4ITGB1CTSAP2RX7MEN1 | |
| SCHEMBL5700856 | 0.89 | ITGB1 (0.71) | ITGA4ITGB1CTSAP2RX7MEN1 | |
| SCHEMBL7426550 | 0.88 | ITGA4 (0.64) | ITGA4ITGB1MEN1KMT2A | |
| SCHEMBL7651159 | 0.88 | ITGB1 (0.64) | ITGA4ITGB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |