Sugi Predict

Sugi Predict / Compounds / Benzamide

Benzamide

Benzamide

SCHEMBL7583369

COc1ccc(S(=O)(=O)Nc2ncnc(OCCO)c2Oc2cccc(OC)c2)cc1.NC(=O)c1ccccc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ EDNRA P25101 3/20 0.72
▸ EDNRB P24530 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzamide SCHEMBL7585785 0.93 EDNRA (0.85) EDNRAEDNRB
SCHEMBL7583371 0.85 EDNRA (0.58) EDNRAEDNRB
SCHEMBL2678965 0.84 EDNRA (1.00) EDNRAEDNRB
SCHEMBL30057758 0.84 EDNRA (1.00) EDNRAEDNRB
Benzamide SCHEMBL7592195 0.84 EDNRA (0.69) EDNRAEDNRB
SCHEMBL7946062 0.83 EDNRA (0.61) EDNRAEDNRB
Benzamide SCHEMBL7582224 0.81 EDNRA (0.87) EDNRAEDNRB
SCHEMBL7589737 0.80 EDNRA (0.62) EDNRAEDNRB
SCHEMBL7591783 0.80 EDNRA (0.61) EDNRAEDNRB
SCHEMBL8656334 0.80 EDNRA (0.92) EDNRAEDNRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0768304-B1 N-(Pyrimidinyl)-benzenesulfonamides as medicaments HOFFMANN LA ROCHE (CH) 2002-05-22 — — EP claimed