Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670453 | 0.83 | HTR2A (0.47) | TP53NPC1RAB9AMAP3K14TSHR | |
| SCHEMBL1539261 | 0.80 | NPC1 (0.36) | NPC1RAB9AALDH1A1HTR2AHTR2C | |
| SCHEMBL7921629 | 0.80 | CYP3A4 (0.45) | NPC1RAB9ATSHRALDH1A1CYP3A4 | |
| SCHEMBL478331 | 0.80 | NPC1 (0.36) | TP53NPC1RAB9AMAP3K14TSHR | |
| SCHEMBL30601262 | 0.80 | NPC1 (0.36) | TP53NPC1RAB9AMAP3K14TSHR | |
| SCHEMBL2422640 | 0.80 | HSD17B10 (0.43) | NPC1RAB9AMAP3K14TSHRALDH1A1 | |
| SCHEMBL8359750 | 0.80 | TSHR (0.45) | TP53NPC1RAB9ATSHRALDH1A1 | |
| SCHEMBL7049820 | 0.77 | TP53 (0.42) | TP53SLC9A1TSHRALDH1A1CYP3A4 | |
| SCHEMBL31725748 | 0.76 | MAP3K14 (0.39) | NPC1RAB9AMAP3K14TSHRCHRNB2 | |
| SCHEMBL3202257 | 0.76 | KIF11 (0.38) | NPC1RAB9AALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |