SCHEMBL758351

SCHEMBL758351

Cc1cc(C)c(O)c(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
KDM4E B2RXH2 4/20 1.00
LMNA P02545 2/20 1.00
GAA P10253 2/20 1.00
MAPT P10636 2/20 1.00
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
PKM P14618 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
SELL P14151 1/20 0.43
SELP P16109 1/20 0.43
SELE P16581 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
TSHR P16473 3/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
NOS2 P35228 1/20 0.41
TP53 P04637 3/20 0.40
CYP3A4 P08684 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29872567 1.00 ALDH1A1 (1.00) ALDH1A1KDM4ELMNAGAAMAPT
Hydrochloric Acid SCHEMBL30811564 0.97 ALDH1A1 (0.95) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL14163474 0.86 ALDH1A1 (0.75) ALDH1A1KDM4ELMNAGAAMAPT
Hydrochloric Acid SCHEMBL11866949 0.83 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAGAAMAPT
Methylamine SCHEMBL18641326 0.80 ALDH1A1 (0.67) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL36529 0.80 ALDH1A1 (0.65) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL27800318 0.80 ALDH1A1 (0.65) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL13993945 0.79 ALDH1A1 (0.65) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL1285862 0.79 ALDH1A1 (0.65) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL2809002 0.79 ALDH1A1 (0.65) ALDH1A1KDM4ELMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116695435-A Carbon fiber, preparation method thereof and composite material containing carbon fiber 江苏君澄空间科技有限公司 2023-09-05 CN claimed
US-5223373-A Positive working photosensitive composition and photosensitive electrodeposition composition prepared therefrom INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 1993-06-29 US claimed
US-5052513-A Heat resistant resin having viscoelasticity properties SHOWA DENKO KABUSHIKI KAISHA (JP) 1991-10-01 US claimed
EP-0269116-A2 Noise reductive resin muffler for exhaust system in combustion engine SHOWA DENKO KABUSHIKI KAISHA (JP) 1988-06-01 EP claimed
EP-4543863-A1 FERROPTOSIS INHIBITORS AND USES THEREOF University Of Ottawa (CA) 2025-04-30 EP disclosed
WO-2025054431-A1 BENZO-FUSED HETEROCYCLIC COMPOUNDS AND USES THEREOF XENON PHARMACEUTICALS INC. (CA) 2025-03-13 WO disclosed
CN-119350386-A Metal compound containing dihydronaphthalene structure and preparation method and application thereof 万华化学集团股份有限公司 2025-01-24 CN disclosed
US-12195469-B2 Compounds having PDE9A inhibitory activity, and pharmaceutical uses thereof KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-01-14 US disclosed
CN-118994228-A Vanadium-imine [ ONO ] tridentate complex and preparation method and application thereof 天津大学 2024-11-22 CN disclosed
EP-3892623-B1 COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF KOREA RES INST CHEMICAL TECH (KR) 2024-07-10 EP disclosed
WO-2023245297-A1 FERROPTOSIS INHIBITORS AND USES THEREOF UNIVERSITY OF OTTAWA (CA) 2023-12-28 WO disclosed
WO-2023245297-A1 FERROPTOSIS INHIBITORS AND USES THEREOF UNIVERSITY OF OTTAWA (CA) 2023-12-28 WO disclosed
EP-0042536-A1 Benzoxozolyldihydronaphthotiophene compounds and their use as optical brighteners BAYER AG (DE) 1981-12-30 EP disclosed
US-4297234-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1981-10-27 US disclosed
EP-0031296-A1 Method for the preparation of benzazolyl compounds CIBA-GEIGY AG (CH) 1981-07-01 EP disclosed
EP-0020298-A1 Benzoxazolyl stilbenes, process for their preparation and their use as optical brighteners for organic materials CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed
US-4119634-A BRIGHTENERS FOR PLASTICS AND POLYESTERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-10 US disclosed
US-4110246-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-08-29 US disclosed
US-4096157-A PIGMENTS HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-20 US disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12195469-B2 Compounds having PDE9A inhibitory activity, and pharmaceutical uses thereof PDE9A, PDE5A, PDE3A ALDH1A1 517/4885KDM4E 930/4885LMNA 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.