Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CBS | P35520 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | SGMS1 | Q86VZ5 | 3/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6289477 | 0.69 | CYP3A4 (0.42) | FFAR1ACHEMEN1KMT2AALDH1A1 | |
| SCHEMBL9350983 | 0.66 | FFAR1 (0.52) | PLA2G2APLA2G5FFAR1ACHEMEN1 | |
| SCHEMBL31040550 | 0.65 | FFAR1 (0.69) | PLA2G2APLA2G5FFAR1CBSACHE | |
| SCHEMBL14924223 | 0.65 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1MEN1KMT2A | |
| Didodecanoylphloroglucinol SCHEMBL9188500 | 0.65 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1MEN1KMT2A | |
| SCHEMBL9752843 | 0.65 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1MEN1KMT2A | |
| SCHEMBL9752712 | 0.65 | PLA2G2A (1.00) | PLA2G2APLA2G5FFAR1MEN1KMT2A | |
| SCHEMBL31040531 | 0.65 | FFAR1 (0.69) | PLA2G2APLA2G5FFAR1CBSACHE | |
| SCHEMBL31040540 | 0.65 | FFAR1 (0.69) | PLA2G2APLA2G5FFAR1CBSACHE | |
| SCHEMBL8394461 | 0.64 | CA12 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462179-B1 | CONJUGATION TO PEPTIDES, PROTEINS, HORMONES, POLYSACCHARIDES, NUCLEIC ACIDS, HAPTENS, DRUGS, LIGANDS, TOXINS, HALOPHORS, AND OTHER MACROMOLECULES | PROLINX, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-0915832-B1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX INC (US) | 2002-10-02 | — | — | EP | disclosed |
| US-6124471-A | Phenyldiboronic acid reagents and complexes | PROLINX, INC. (US) | 2000-09-26 | — | — | US | disclosed |
| US-6075126-A | Phenyldiboronic acid reagents and complexes | PROLINX, INC. (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0915832-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005627-A1 | BORONIC COMPOUND COMPLEXING REAGENTS AND HIGHLY STABLE COMPLEXES | PROLINX, INC. (US) | 1998-02-12 | — | — | WO | disclosed |