Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.77 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7214979 | 0.96 | DNM1 (0.81) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Bromide SCHEMBL126636 | 0.96 | DNM1 (0.81) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Bromide SCHEMBL302420 | 0.96 | DNM1 (0.81) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Iodide SCHEMBL187956 | 0.96 | DNM1 (0.75) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Phosphine SCHEMBL27291545 | 0.93 | DNM1 (0.77) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Methane SCHEMBL27372554 | 0.93 | DNM1 (0.77) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Bromide SCHEMBL27382254 | 0.93 | DNM1 (0.77) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27513587 | 0.93 | DNM1 (0.77) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| Bromide SCHEMBL8509102 | 0.93 | DNM1 (0.77) | DNM1BDKRB2TSHRLMNAALDH1A1 | |
| SCHEMBL29496398 | 0.93 | DNM1 (0.80) | DNM1BDKRB2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009546-B1 | SUBSTRATE HAVING A MULTILAYER COAT AND METHOD FOR ITS PRODUCTION | BASF COATINGS AG (DE) | 2002-10-02 | — | — | EP | disclosed |
| US-6426147-B1 | SUBSTRATE, DECORATION LAYER, PROTECTIVE COATING | BASF COATINGS AG (DE) | 2002-07-30 | — | — | US | disclosed |
| EP-1009546-A1 | SUBSTRATE HAVING A MULTILAYER COAT AND METHOD FOR ITS PRODUCTION | BASF Coatings AG (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999008808-A1 | SUBSTRATE HAVING A MULTILAYER COAT AND METHOD FOR ITS PRODUCTION | BASF COATINGS AG (DE) | 1999-02-25 | — | — | WO | disclosed |
| US-4835225-A | Modified advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1989-05-30 | — | — | US | disclosed |
| US-4820784-A | CURED HOMO- AND COPOLYMERS OF POLYEPOXIDES, EPOXY RESINS AND POLYETHERS MODIFIED BY PHOSPHORIC ACID; LOW VISCOSITY; FLEXIBLE CHEMICAL RESISTANCE COATINGS | THE DOW CHEMICAL COMPANY (US) | 1989-04-11 | — | — | US | disclosed |