Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3632915 | 0.80 | KDM4E (0.50) | LMNAKMT2ADPP4 | |
| SCHEMBL22718801 | 0.80 | CYP2D6 (0.38) | LMNACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20693674 | 0.79 | DPP4 (0.46) | LMNAPIM1SIRT6CYP2D6CHEK2 | |
| SCHEMBL2254372 | 0.79 | POLB (0.47) | LMNAPIM1SIRT6CHEK2KMT2A | |
| SCHEMBL9696316 | 0.78 | CYP2D6 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL27882830 | 0.78 | KDM4E (0.48) | LMNAKMT2ADPP4 | |
| SCHEMBL28199674 | 0.78 | F10 (0.36) | LMNACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6630545 | 0.78 | BAZ2B (0.33) | LMNACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9722614 | 0.78 | CYP2D6 (0.38) | LMNACYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22169011 | 0.75 | LMNA (0.41) | LMNAPIM1SIRT6CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1246802-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051468-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-19 | — | — | WO | disclosed |
| EP-1114045-A1 | 2-METHOXYIMINO-2-(PYRIDINYLOXYMETHYL)PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | Dow AgroSciences LLC (US) | 2001-07-11 | — | — | EP | disclosed |
| WO-2000015637-A1 | 2-METHOXYIMINO -2-(PYRIDINYLOXYMETHYL) PHENYL ACETAMIDES WITH 5 MEMBERED HETEROCYCLIC RINGS ON THE PYRIDINE RING AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2000-03-23 | — | — | WO | disclosed |