Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583001 | 0.81 | ALDH1A1 (0.41) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7582531 | 0.81 | NPC1 (0.39) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7583720 | 0.80 | MAPT (0.42) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8415982 | 0.80 | MAPT (0.42) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6988543 | 0.75 | TAAR1 (0.51) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6982915 | 0.71 | ALDH1A1 (0.38) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6982917 | 0.70 | ALDH1A1 (0.41) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9627687 | 0.69 | TAAR1 (0.62) | MAPTALDH1A1SMN1; SMN2TAAR1INPP5D | |
| SCHEMBL8602601 | 0.67 | NPC1 (0.37) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL2783728 | 0.67 | TAAR1 (0.62) | NPC1MAPTALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939755-B1 | OXAZOLINE ARTHROPODICIDES | PURDUE RESEARCH FOUNDATION (US) | 2002-10-09 | — | — | EP | claimed |
| US-6107319-A | PESTICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-22 | — | — | US | claimed |
| EP-0939755-B1 | OXAZOLINE ARTHROPODICIDES | PURDUE RESEARCH FOUNDATION (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6107319-A | PESTICIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| EP-0939755-A1 | OXAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1997026249-A1 | OXAZOLINE ARTHROPODICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-07-24 | — | — | WO | disclosed |