Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20113370 | 0.80 | USP8 (0.35) | KDM4EALDH1A1POLBEGLN2CYP11B1 | |
| SCHEMBL2596849 | 0.80 | KDM4E (0.32) | KDM4EALDH1A1POLBEGLN2 | |
| SCHEMBL29368821 | 0.80 | USP8 (0.35) | KDM4EALDH1A1POLBEGLN2CYP11B1 | |
| SCHEMBL24455335 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1POLBCYP11B1CYP11B2 | |
| SCHEMBL27946108 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1POLBEGLN2SYK | |
| SCHEMBL30555131 | 0.70 | USP8 (0.35) | EGLN2 | |
| SCHEMBL24455466 | 0.70 | USP8 (0.35) | EGLN2 | |
| SCHEMBL29877981 | 0.70 | KDM4E (0.32) | KDM4EALDH1A1POLB | |
| SCHEMBL12498325 | 0.70 | EGLN2 (0.36) | KDM4EALDH1A1POLBEGLN2CYP11B1 | |
| SCHEMBL6486674 | 0.70 | TRPV4 (0.37) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668163-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| EP-2667712-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| EP-2667713-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED)PICOLINATES | Dow AgroSciences LLC (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012103041-A2 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED) PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012103044-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-3-CHLORO-5-FLUORO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012103045-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-5-FLUORO-3-HALO-6-(SUBSTITUTED)PICOLINATES | DOW AGROSCIENCES LLC (US) | 2012-08-02 | — | — | WO | disclosed |
| EP-1246802-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001051468-A1 | 4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-19 | — | — | WO | disclosed |