Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CPA1 | P15085 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20579813 | 0.78 | CA1 (0.41) | CA1RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL1200181 | 0.77 | RNPEP (0.57) | RNPEPSLC7A5SLC1A3SLC1A2ALDH1A1 | |
| SCHEMBL27797298 | 0.76 | CA1 (0.48) | CA1RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL29571242 | 0.74 | RNPEP (0.44) | RNPEPSLC7A5SLC1A3SLC1A2ALDH1A1 | |
| SCHEMBL106832 | 0.74 | CA1 (0.46) | CA1RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL5143583 | 0.74 | RNPEP (0.44) | RNPEPSLC7A5SLC1A3SLC1A2FOLH1 | |
| SCHEMBL14896184 | 0.73 | CA1 (0.44) | CA1SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL800723 | 0.72 | CA1 (0.55) | CA1SLC1A3SLC1A2SLC1A1CYP1A2 | |
| Hydroxyamine SCHEMBL20817080 | 0.72 | SLC7A5 (0.59) | RNPEPSLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10961166 | 0.71 | RNPEP (0.41) | RNPEPSLC7A5SLC1A3SLC1A2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1279053-C | Modulators for beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARM INC (US) | 2006-10-11 | — | — | CN | disclosed |
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2000052048-A9 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-1161449-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 2001-12-12 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000052048-A1 | MODULATORS OF BETA-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2000-09-08 | — | — | WO | disclosed |
| EP-0929574-A1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | Praecis Pharmaceuticals Incorporated (US) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998008868-A9 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | — | 1998-05-28 | — | — | WO | disclosed |
| WO-1998008868-A1 | MODULATORS OF β-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 1998-03-05 | — | — | WO | disclosed |