Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 3/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1200181 | 0.79 | RNPEP (0.57) | RNPEPSLC7A5ALDH1A1CPA1MEN1 | |
| SCHEMBL28652007 | 0.79 | MME (0.33) | RNPEPSLC7A5ALDH1A1MMEFOLH1 | |
| SCHEMBL29571242 | 0.76 | RNPEP (0.44) | RNPEPSLC7A5ALDH1A1CPA1MEN1 | |
| SCHEMBL31502287 | 0.76 | RNPEP (0.39) | RNPEPSLC7A5ALDH1A1CPA1MEN1 | |
| SCHEMBL7684983 | 0.75 | LDHA (0.40) | ALDH1A1CPA1MEN1KMT2AMME | |
| SCHEMBL7585174 | 0.74 | CA1 (0.44) | RNPEPSLC7A5ALDH1A1CPA1MEN1 | |
| SCHEMBL9638836 | 0.74 | RNPEP (0.60) | RNPEPSLC7A5ALDH1A1CPA1MEN1 | |
| SCHEMBL9819868 | 0.74 | SLC7A5 (0.60) | RNPEPSLC7A5ALDH1A1CACNA2D1CACNB3 | |
| SCHEMBL10536292 | 0.74 | SLC7A5 (0.60) | RNPEPSLC7A5ALDH1A1CACNA2D1CACNB3 | |
| Hydroxyamine SCHEMBL20817080 | 0.74 | SLC7A5 (0.59) | RNPEPSLC7A5ALDH1A1CPA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301031-B2 | Methods for producing hydroxy amino acids, esters, and derivatives thereof | BIOCATALYTICS, INC. (US) | 2007-11-27 | — | — | US | disclosed |
| US-7081535-B2 | Hydroxy-amino acids | BIOCATALYTICS, INC. (US) | 2006-07-25 | — | — | US | disclosed |
| US-20050192439-A1 | Methods for producing hydroxy amino acids, esters, and derivatives thereof | CODEXIS, INC. | 2005-09-01 | — | — | US | disclosed |
| US-20050100993-A1 | Methods for producing hydroxy amino acids and derivatives thereof | BIOCATALYTICS, INC. | 2005-05-12 | — | — | US | disclosed |
| US-6833471-B2 | Contacting beta-ketodiester having ketone and two esters with a ketoreductase under conditions permitting reduction of ketone to alcohol, regioselectively hydrolyzing one of ester groups to acid, converting acid or ester to amine | BIOCATALYTICS, INC. | 2004-12-21 | — | — | US | disclosed |
| US-20040053377-A1 | Methods for producing hydroxy amino acids and derivatives thereof | CODEXIS, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053377-A1 | Methods for producing hydroxy amino acids and derivatives thereof | HMGCR, HSD17B12, BCKDK | RNPEP 141/4885SLC7A5 347/4885ALDH1A1 514/4885 |
| US-20050100993-A1 | Methods for producing hydroxy amino acids and derivatives thereof | ALDH7A1, BCKDK, HSD17B12 | RNPEP 319/4885SLC7A5 344/4885ALDH1A1 130/4885 |
| US-20050192439-A1 | Methods for producing hydroxy amino acids, esters, and derivatives thereof | ALDH7A1, BCKDK, ADH5 | RNPEP 355/4885SLC7A5 461/4885ALDH1A1 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.