Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5853930 | 0.90 | PTPN1 (0.41) | PTPN1TMEM97HTR2BSIGMAR1CYP19A1 | |
| SCHEMBL7587937 | 0.85 | PPARG (0.36) | PTPN1TMEM97HTR2BSIGMAR1ESR1 | |
| SCHEMBL7592872 | 0.84 | PPARG (0.35) | PTPN1TMEM97HTR2BSIGMAR1ESR1 | |
| SCHEMBL5854374 | 0.83 | PTPN1 (0.35) | PTPN1TMEM97HTR2BSIGMAR1CYP19A1 | |
| SCHEMBL8520541 | 0.81 | PPARG (0.33) | PTPN1TMEM97HTR2BSIGMAR1PPARG | |
| SCHEMBL5854922 | 0.80 | PTPN1 (0.33) | PTPN1TMEM97HTR2BSIGMAR1 | |
| SCHEMBL7587424 | 0.77 | ESR1 (0.32) | ESR1ESR2PPARGPPARDHTR1A | |
| SCHEMBL27560344 | 0.77 | PTPN1 (0.40) | PTPN1TMEM97HTR2BSIGMAR1CYP19A1 | |
| SCHEMBL5854163 | 0.76 | PTPN1 (0.37) | PTPN1TMEM97HTR2BSIGMAR1PPARG | |
| SCHEMBL5856130 | 0.76 | HRH3 (0.42) | ALDH1A1ESR1ESR2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |