Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARD | Q03181 | 12/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520541 | 0.96 | PPARG (0.33) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL7592872 | 0.92 | PPARG (0.35) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL5854374 | 0.89 | PTPN1 (0.35) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL7585408 | 0.85 | PTPN1 (0.40) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL7587424 | 0.84 | ESR1 (0.32) | PPARGPPARDESR1PGRCHRM2 | |
| SCHEMBL5853930 | 0.81 | PTPN1 (0.41) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL5856130 | 0.80 | HRH3 (0.42) | MAOBESR1PGRCHRM2HTR1A | |
| SCHEMBL5856132 | 0.80 | ITGB3 (0.38) | PPARGPPARDFFAR1HTR2BTMEM97 | |
| SCHEMBL8520859 | 0.79 | PPARG (0.30) | PPARGPPARDESR1 | |
| SCHEMBL5854922 | 0.77 | PTPN1 (0.33) | HTR2BTMEM97SIGMAR1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |