Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13430949 | 0.81 | MPI (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL215097 | 0.81 | MPI (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL2884877 | 0.81 | MPI (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL426315 | 0.81 | MPI (0.36) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL7068623 | 0.79 | MPI (0.37) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL7070578 | 0.79 | MPI (0.37) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL7066959 | 0.79 | MPI (0.37) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL7583195 | 0.79 | TDP1 (0.47) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL7587235 | 0.79 | TDP1 (0.34) | TDP1USP2CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL9617279 | 0.79 | PAX8 (0.38) | TDP1USP2CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798309-B1 | Diagnostic agent for glycometabolic function | NIHON MEDIPHYSICS CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-5904915-A | MEDICAL DIAGNOSIS OF TUMORS | NIHON MEDI-PHYSICS CO., LTD. (JP) | 1999-05-18 | — | — | US | disclosed |
| EP-0798309-A1 | Diagnostic agent for glycometabolic function | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 1997-10-01 | — | — | EP | disclosed |