SCHEMBL7585617

SCHEMBL7585617

COc1cc(C(=O)N2CCN(Cc3cncn3Cc3ccc(C#N)cc3)CC2)ccc1C.N#Cc1ccc(Cn2cncc2CN2CCN(C(=O)c3ccc4ccccc4n3)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.56
FNTB P49356 20/20 0.56
PGGT1B P53609 17/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7481000 0.90 FNTA (0.63) FNTAFNTBPGGT1B
SCHEMBL7590096 0.88 FNTA (0.63) FNTAFNTBPGGT1B
SCHEMBL7747202 0.81 FNTA (0.62) FNTAFNTBPGGT1B
SCHEMBL7588726 0.78 FNTA (0.60) FNTAFNTBPGGT1B
SCHEMBL7589813 0.76 FNTA (0.66) FNTAFNTBPGGT1B
SCHEMBL7487655 0.76 FNTA (0.60) FNTAFNTBPGGT1B
SCHEMBL7483644 0.76 FNTA (0.57) FNTAFNTBPGGT1B
Hydrochloric Acid SCHEMBL7570758 0.76 FNTA (0.59) FNTAFNTBPGGT1B
SCHEMBL7590122 0.74 FNTA (0.57) FNTAFNTBPGGT1B
SCHEMBL7487074 0.73 FNTA (0.66) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020072081-A1 Geranylgeranyl transferase inhibitor screening assay ENG WAI-SI (US) 2002-06-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072081-A1 Geranylgeranyl transferase inhibitor screening assay GGT1, FNTA, GGPS1 FNTA 2/4885FNTB 7/4885PGGT1B 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.