⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11135283 | 0.96 | THRB (0.32) | — | |
| SCHEMBL3971564 | 0.85 | — | — | |
| SCHEMBL514670 | 0.83 | — | — | |
| SCHEMBL236251 | 0.83 | — | — | |
| SCHEMBL13745145 | 0.83 | — | — | |
| SCHEMBL13745144 | 0.83 | — | — | |
| SCHEMBL15624617 | 0.83 | — | — | |
| SCHEMBL2565232 | 0.83 | — | — | |
| SCHEMBL18973986 | 0.81 | — | — | |
| SCHEMBL22789862 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106535876-B | Multivalent delivery of immunomodulators through liposomal spherical nucleic acids for prophylactic or therapeutic applications | 埃克西奎雷股份有限公司 | 2020-09-11 | — | — | CN | claimed |
| EP-3084433-B1 | METHOD OF IMMOBILIZING A CELL ON A SUPPORT USING COMPOUNDS COMPRISING A POLYETHYLENE GLYCOL MOIETY | ROCHE DIAGNOSTICS GMBH (DE) | 2020-03-18 | — | — | EP | claimed |
| EP-3164113-B1 | MULTIVALENT DELIVERY OF IMMUNE MODULATORS BY LIPOSOMAL SPHERICAL NUCLEIC ACIDS FOR PROPHYLACTIC OR THERAPEUTIC APPLICATIONS | EXICURE INC (US) | 2019-03-27 | — | — | EP | claimed |
| EP-3084431-B1 | COMPOUNDS COMPRISING ONE OR MORE HYDROPHOBIC DOMAINS AND A HYDROPHILIC DOMAIN COMPRISING PEG MOIETIES, USEFUL FOR BINDING CELLS | ROCHE DIAGNOSTICS GMBH (DE) | 2018-11-07 | — | — | EP | claimed |
| US-20160355859-A1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK A/S (DK) | 2016-12-08 | — | — | US | claimed |
| EP-2033662-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2012-10-17 | — | — | EP | claimed |
| EP-2368579-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2011-09-28 | — | — | EP | claimed |
| US-20100009917-A1 | Modulating Enzymatic Processes by Addition of Diolcontaining Substances | NOVO NORDISK HEALTH CARE AG (CH) | 2010-01-14 | — | — | US | claimed |
| US-20090264366-A1 | Transglutaminase Mediated Conjugation of Peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2009-10-22 | — | — | US | claimed |
| EP-2033662-A1 | Transglutaminase mediated conjugation of peptides | Novo Nordisk Health Care AG (CH) | 2009-03-11 | — | — | EP | claimed |
| US-20070105770-A1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK A/S (DK) | 2007-05-10 | — | — | US | claimed |
| US-11965886-B2 | Method of immobilizing a cell on a support using compounds comprising a polyethylene glycol moiety | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2024-04-23 | — | — | US | disclosed |
| WO-2022210788-A1 | PHOTOSENSITIVE RESIN COMPOSITION | 味の素株式会社 | 2022-10-06 | — | — | WO | disclosed |
| CN-106535876-B | Multivalent delivery of immunomodulators through liposomal spherical nucleic acids for prophylactic or therapeutic applications | 埃克西奎雷股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| EP-2842576-B1 | Transglutaminase mediated conjugation of peptides | NOVO NORDISK HEALTHCARE AG (CH) | 2017-06-28 | — | — | EP | disclosed |
| US-20060154984-A1 | Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof | GENFIT (FR) | 2006-07-13 | — | — | US | disclosed |
| US-20060069156-A1 | Acylated aminopropanediols and analogues and therapeutic uses thereof | GENFIT (FR) | 2006-03-30 | — | — | US | disclosed |
| US-20060035977-A1 | Uses of acylated aminopropanediols and sulphur and nitrogen analogues of same f | GENTIF (FR) | 2006-02-16 | — | — | US | disclosed |
| EP-1596845-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | Genfit (FR) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004073698-A1 | THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF | GENFIT (FR) | 2004-09-02 | — | — | WO | disclosed |