Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | BHMT | Q93088 | 6/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | MARS1 | P56192 | 5/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | ARG1 | P05089 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7588933 | 0.81 | SLC7A5 (0.43) | RNPEPBHMTBHMT2METAP2METAP1 | |
| SCHEMBL8014740 | 0.76 | PTGS1 (0.45) | — | |
| SCHEMBL7592092 | 0.75 | BHMT (0.39) | RNPEPBHMTBHMT2METAP2METAP1 | |
| SCHEMBL15756564 | 0.74 | RNPEP (0.44) | RNPEPMETAP2METAP1FNTAFNTB | |
| Racemethionine SCHEMBL23361966 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL23361956 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL23361947 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL23648682 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL23361938 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 | |
| Racemethionine SCHEMBL23361946 | 0.72 | BHMT (0.52) | RNPEPBHMTBHMT2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438600-B2 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6156555-A | Method of preparing an enzyme participating in C-terminal amidation | SHISEIDO COMPANY LTD. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0666318-B1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO CO LTD (JP) | 2000-11-29 | — | — | EP | disclosed |
| US-5871995-A | Purified enzymes participating in C-terminal amidation | SHISEIDO COMPANY, LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0884389-A1 | Enzyme participating in C-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1998-12-16 | — | — | EP | disclosed |
| EP-0438600-B1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO CO LTD (JP) | 1996-02-07 | — | — | EP | disclosed |
| EP-0666318-A1 | Enzyme participating in c-terminal amidation, and method of preparing same and use thereof | SHISEIDO COMPANY LIMITED (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0438600-A1 | ENZYMES WHICH PARTICIPATE IN C-TERMINAL AMIDATION, AND PRODUCTION AND USE THEREOF | SHISEIDO COMPANY LIMITED (JP) | 1991-07-31 | — | — | EP | disclosed |