Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586262 | 1.00 | RXRA (0.53) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6478159 | 0.91 | RECQL (0.52) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6478156 | 0.91 | RECQL (0.52) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6473263 | 0.91 | RXRA (0.67) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6473269 | 0.91 | RXRA (0.67) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6476283 | 0.91 | RXRA (0.47) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6476290 | 0.91 | RXRA (0.47) | RXRAKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL6472485 | 0.90 | KDM4E (0.54) | RXRAKDM4ECYP26A1CYP26B1AKR1C3 | |
| SCHEMBL6472482 | 0.90 | KDM4E (0.54) | RXRAKDM4ECYP26A1CYP26B1AKR1C3 | |
| SCHEMBL6473182 | 0.89 | KDM4E (0.53) | RXRAKDM4EALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947496-B1 | Bicyclic aromatic compounds and their use in human and veterinary medicine as well as in cosmetology | GALDERMA RES & DEV (FR) | 2002-10-09 | — | — | EP | disclosed |
| EP-0947496-A1 | Bicyclic aromatic compounds and their use in human and veterinary medicine as well as in cosmetology | Galderma Research & Development, S.N.C. (FR) | 1999-10-06 | — | — | EP | disclosed |