Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | GABBR2 | O75899 | 4/20 | 0.50 |
| ▸ | GABBR1 | Q9UBS5 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855617 | 0.85 | CES2 (0.61) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL29772071 | 0.83 | CES2 (0.59) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL15120380 | 0.83 | CES2 (0.59) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL761473 | 0.83 | CES2 (0.59) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL3957744 | 0.83 | CES2 (0.59) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL15385170 | 0.81 | CES2 (0.57) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL29645049 | 0.81 | CES1 (0.61) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL4307207 | 0.81 | CES1 (0.61) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL7203368 | 0.80 | CES2 (0.55) | CES2CES1GABBR2GABBR1SMN1; SMN2 | |
| SCHEMBL29137246 | 0.79 | CES2 (0.59) | CES2CES1GABBR2GABBR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776011-B1 | FUNGICIDAL COMPOSITION CONTAINING AN ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA (JP) | 2012-03-21 | — | — | EP | disclosed |
| US-8039420-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-7829501-B2 | Fungicidal composition containing acid amide derivative | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-10-14 | — | — | US | disclosed |
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | ISHIHARA SANGYO KAISHA LTD (JP) | 2008-12-25 | — | — | US | disclosed |
| EP-1776011-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016708-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318779-A1 | N-[(4'-methoxy-2'-methyl-1,1-dimethyl)phenacyl]-3-methyl-2-thiophenecarboxamide and another fungicide or an antibiotic; controlling noxious fungi at a low dose; Oomycetes, Ascomycetes, Basidiomycetes, Deuteromycetes particularly effective against Ascomycetes or Deuteromycetes; plant diseases | AADAC, NAT1, TH | CES2 1540/4885CES1 1031/4885GABBR2 1119/4885 |
| US-20100261675-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | CES2 437/4885CES1 547/4885GABBR2 211/4885 |
| US-20100261735-A1 | FUNGICIDAL COMPOSITION CONTAINING ACID AMIDE DERIVATIVE | CBR3, AADAC, NAT1 | CES2 437/4885CES1 547/4885GABBR2 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.