Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 20/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7579281 | 0.95 | PLA2G7 (0.88) | PLA2G7 | |
| SCHEMBL7586031 | 0.91 | PLA2G7 (0.96) | PLA2G7CYP3A4 | |
| SCHEMBL7598574 | 0.88 | PLA2G7 (1.00) | PLA2G7 | |
| Hydrochloric Acid SCHEMBL4419455 | 0.85 | PLA2G7 (0.87) | PLA2G7CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4415693 | 0.84 | PLA2G7 (1.00) | PLA2G7CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4424698 | 0.84 | PLA2G7 (0.83) | PLA2G7CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL4415555 | 0.83 | PLA2G7 (1.00) | PLA2G7CYP3A4CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7583537 | 0.82 | PLA2G7 (0.86) | PLA2G7 | |
| SCHEMBL7576977 | 0.82 | PLA2G7 (0.84) | PLA2G7 | |
| SCHEMBL4422099 | 0.82 | PLA2G7 (1.00) | PLA2G7CYP3A4CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173424-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066566-A1 | PYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2000-11-09 | — | — | WO | disclosed |