SCHEMBL7586522

SCHEMBL7586522

CCCCCCCCCNc1nc2ccccc2[nH]1

nearest known ligand 0.88

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.88
TRPC3 Q13507 1/20 0.88
TRPC4 Q9UBN4 1/20 0.88
TRPC5 Q9UL62 1/20 0.88
TSHR P16473 2/20 0.68
SPHK2 Q9NRA0 1/20 0.61
SPHK1 Q9NYA1 1/20 0.61
RAB9A P51151 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
ALDH1A1 P00352 2/20 0.59
NPC1 O15118 1/20 0.59
TDP1 Q9NUW8 1/20 0.56
TP53 P04637 1/20 0.55
CCNT1 O60563 1/20 0.52
CDK9 P50750 1/20 0.52
RIPK1 Q13546 1/20 0.52
KCNH2 Q12809 1/20 0.51
BACE1 P56817 1/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27915816 1.00 BCHE (0.88) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL673939 0.98 BCHE (0.91) BCHETRPC3TRPC4TRPC5TSHR
Hydrochloric Acid SCHEMBL28115259 0.97 BCHE (0.88) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL22619945 0.94 BCHE (1.00) BCHETRPC3TRPC4TRPC5TSHR
Hydrochloric Acid SCHEMBL23295188 0.92 BCHE (0.97) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL8464091 0.87 BCHE (0.82) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL6439777 0.85 BCHE (0.68) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL4640893 0.83 BCHE (0.70) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL6034415 0.81 BCHE (0.72) BCHETRPC3TRPC4TRPC5TSHR
SCHEMBL14068347 0.81 BCHE (0.72) BCHETRPC3TRPC4TRPC5TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002074085-A1 NEORUSTMICIN A-DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 2002-09-26 WO disclosed
EP-1083790-A1 RETARDING FORMULATIONS OF ACTIVE SUBSTANCES USED FOR PLANT PROTECTION BASF AKTIENGESELLSCHAFT (DE) 2001-03-21 EP disclosed
WO-1999056540-A1 RETARDING FORMULATIONS OF ACTIVE SUBSTANCES USED FOR PLANT PROTECTION BASF AKTIENGESELLSCHAFT (DE) 1999-11-11 WO disclosed