Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.91 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.91 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.91 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.91 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586522 | 0.98 | BCHE (0.88) | BCHETRPC3TRPC4TRPC5TSHR | |
| Hydrochloric Acid SCHEMBL28115259 | 0.98 | BCHE (0.88) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL27915816 | 0.98 | BCHE (0.88) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL22619945 | 0.95 | BCHE (1.00) | BCHETRPC3TRPC4TRPC5TSHR | |
| Hydrochloric Acid SCHEMBL23295188 | 0.94 | BCHE (0.97) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL8464091 | 0.89 | BCHE (0.82) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL4640893 | 0.84 | BCHE (0.70) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL6439777 | 0.83 | BCHE (0.68) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL8492186 | 0.83 | BCHE (0.72) | BCHETRPC3TRPC4TRPC5TSHR | |
| SCHEMBL6034415 | 0.83 | BCHE (0.72) | BCHETRPC3TRPC4TRPC5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 133 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819353-A | Method for preparing 2-aryl amino benzimidazole and N1-aryl-2-amino benzimidazole | 长沙晶易医药科技股份有限公司 | 2023-03-21 | — | — | CN | claimed |
| US-20180282734-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-10-04 | — | — | US | claimed |
| EP-3368034-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | Children's Hospital Medical Center (US) | 2018-09-05 | — | — | EP | claimed |
| CN-106350678-B | A method of recycling corrosion inhibiter and copper from brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-106245058-B | A kind of method of copper in electrolytic recovery brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2018-06-19 | — | — | CN | claimed |
| US-9855273-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-01-02 | — | — | US | claimed |
| EP-2999470-B1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2017-08-16 | — | — | EP | claimed |
| WO-2017075054-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2017-05-04 | — | — | WO | claimed |
| US-20170087162-A1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2017-03-30 | — | — | US | claimed |
| CN-106350678-A | Method of recycling corrosion inhibitor and copper from brownification waste liquid | 盛隆资源再生（无锡）有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-106245058-A | A kind of method of the copper in electrolytic recovery brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2016-12-21 | — | — | CN | claimed |
| US-9504706-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2016-11-29 | — | — | US | claimed |
| CN-105714280-A | Browning treatment liquid for printed circuit board | 武汉创新特科技有限公司 | 2016-06-29 | — | — | CN | claimed |
| EP-2999470-A2 | COMBINATION THERAPY FOR MDS | Children's Hospital Medical Center (US) | 2016-03-30 | — | — | EP | claimed |
| US-20160038529-A1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2016-02-11 | — | — | US | claimed |
| US-9168257-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2015-10-27 | — | — | US | claimed |
| CN-104780764-A | Use of substituted 2-amidobenzimidazoles, 2-amidobenzoxazoles and 2-amidobenzothiazoles or salts thereof as active substances against abiotic plant stress | BAYER CROPSCIENCE AG | 2015-07-15 | — | — | CN | claimed |
| WO-2014190163-A2 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2014-11-27 | — | — | WO | claimed |
| US-20140350070-A1 | Combination Therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2014-11-27 | — | — | US | claimed |
| CN-115819353-B | Method for preparing 2-arylamino benzimidazole and N1-aryl-2-amino benzimidazole | 长沙晶易医药科技股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| CN-115959995-A | Industrial production method of 2,4-difluoronitrobenzene | 云南云天化股份有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115819353-A | Method for preparing 2-aryl amino benzimidazole and N1-aryl-2-amino benzimidazole | 长沙晶易医药科技股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| US-20210292843-A1 | TREATMENT OF DISEASES ASSOCIATED WITH ACTIVATED IRAK | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-09-23 | — | — | US | disclosed |
| EP-3532164-A1 | TREATMENT OF DISEASES ASSOCIATED WITH ACTIVATED IRAK | Children's Hospital Medical Center (US) | 2019-09-04 | — | — | EP | disclosed |
| CN-110029336-A | A kind of multilayer printed circuit board manufacture copper surface treatment liquid and processing method | 电子科技大学 | 2019-07-19 | — | — | CN | disclosed |
| CN-106349167-B | Benzimidizole derivatives phosphate anion fluorescence probe synthesizes and application method | 齐齐哈尔大学 | 2018-10-19 | — | — | CN | disclosed |
| US-20180282734-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-10-04 | — | — | US | disclosed |
| EP-3368034-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | Children's Hospital Medical Center (US) | 2018-09-05 | — | — | EP | disclosed |
| CN-106350678-B | A method of recycling corrosion inhibiter and copper from brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-106245058-B | A kind of method of copper in electrolytic recovery brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-105050324-B | Copper surface roughening treatment liquid and its processing method | 广东光华科技股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| WO-2018081738-A1 | TREATMENT OF DISEASES ASSOCIATED WITH ACTIVATED IRAK | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-05-03 | — | — | WO | disclosed |
| US-9855273-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2018-01-02 | — | — | US | disclosed |
| US-20170240556-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | 4SC DISCOVERY GMBH (DE) | 2017-08-24 | — | — | US | disclosed |
| EP-2999470-B1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2017-08-16 | — | — | EP | disclosed |
| WO-2017075054-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2017-05-04 | — | — | WO | disclosed |
| US-20170087162-A1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2017-03-30 | — | — | US | disclosed |
| US-9580438-B2 | Bifluorodioxalane-amino-benzimidazole kinase inhibitors for the treatment of cancer, autoimmuneinflammation and CNS disorders | 4SC DISCOVERY GMBH (DE) | 2017-02-28 | — | — | US | disclosed |
| CN-106350678-A | Method of recycling corrosion inhibitor and copper from brownification waste liquid | 盛隆资源再生（无锡）有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-106245058-A | A kind of method of the copper in electrolytic recovery brown oxide waste liquid | 盛隆资源再生（无锡）有限公司 | 2016-12-21 | — | — | CN | disclosed |
| US-9504706-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2016-11-29 | — | — | US | disclosed |
| CN-103097359-B | Compounds as microsomal prostaglandin E2 synthase-1 inhibitors | 贝林格尔.英格海姆国际有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105714280-A | Browning treatment liquid for printed circuit board | 武汉创新特科技有限公司 | 2016-06-29 | — | — | CN | disclosed |
| EP-2999470-A2 | COMBINATION THERAPY FOR MDS | Children's Hospital Medical Center (US) | 2016-03-30 | — | — | EP | disclosed |
| US-20160038529-A1 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2016-02-11 | — | — | US | disclosed |
| CN-105050324-A | Copper surface roughening treatment solution and treatment method thereof | GUANGDONG GUANGHUA SCI TECH CO LTD | 2015-11-11 | — | — | CN | disclosed |
| US-9168257-B2 | Combination therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2015-10-27 | — | — | US | disclosed |
| CN-104780764-A | Use of substituted 2-amidobenzimidazoles, 2-amidobenzoxazoles and 2-amidobenzothiazoles or salts thereof as active substances against abiotic plant stress | BAYER CROPSCIENCE AG | 2015-07-15 | — | — | CN | disclosed |
| EP-2649071-B1 | Imidazo(4,5-b)pyridine-6-carboxamides as anti-inflammatory agents | OREXO AB (SE) | 2015-07-08 | — | — | EP | disclosed |
| US-20150158878-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | 4SC DISCOVERY GMBH (DE) | 2015-06-11 | — | — | US | disclosed |
| EP-2867237-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | 4SC Discovery GmbH (DE) | 2015-05-06 | — | — | EP | disclosed |
| WO-2014190163-A2 | COMBINATION THERAPY FOR MDS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2014-11-27 | — | — | WO | disclosed |
| US-20140350070-A1 | Combination Therapy for MDS | CHILDREN'S HOSPITAL MEDICAL CENTER | 2014-11-27 | — | — | US | disclosed |
| EP-2649052-B1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INT (DE) | 2014-10-22 | — | — | EP | disclosed |
| EP-2606036-B1 | 2-ANILINOBENZIMIDAZOLE-6-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-08 | — | — | EP | disclosed |
| US-8759537-B2 | 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| WO-2014001464-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | 4SC DISCOVERY GMBH (DE) | 2014-01-03 | — | — | WO | disclosed |
| US-8586604-B2 | Inhibitors of the microsomal prostaglandin E2 synthase-1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| EP-2649052-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649071-A1 | IMIDAZO(4,5-B)PYRIDINE-6-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| EP-2649051-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| US-8486370-B2 | Heterocyclic ligands for integrin imaging and therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-07-16 | — | — | US | disclosed |
| US-8486968-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-16 | — | — | US | disclosed |
| EP-2606036-A1 | NEW COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-06-26 | — | — | EP | disclosed |
| EP-2606046-A1 | 2-(ARYLAMINO)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBOXAMIDE DERIVATIVES AND THEIR USE AS MPGES-1 INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2013-06-26 | — | — | EP | disclosed |
| US-8466186-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-18 | — | — | US | disclosed |
| US-20120309755-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120309738-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120214786-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
| US-20120208839-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-16 | — | — | US | disclosed |
| WO-2012076674-A1 | IMIDAZO(4,5-B)PYRIDINE-6-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012022793-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| WO-2012022792-A1 | 2-(ARYLAMINO)-3H-IMIDAZO[4,5-B]PYRIDINE-6-CARBOXAMIDE DERIVATIVES AND THEIR USE AS MPGES-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-02-23 | — | — | WO | disclosed |
| EP-2319512-A1 | Novel 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels. | NeuroSearch AS (DK) | 2011-05-11 | — | — | EP | disclosed |
| US-20110034527-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | SOERENSEN ULRIK SVANE | 2011-02-10 | — | — | US | disclosed |
| US-20100331384-A1 | GUANIDINE BASED COMPOUNDS | UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) | 2010-12-30 | — | — | US | disclosed |
| US-20100310455-A1 | Heterocyclic Ligands for Integrin Imaging and Therapy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-09 | — | — | US | disclosed |
| US-7842817-B2 | 2-amino benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels | NEUROSEARCH A/S (DK) | 2010-11-30 | — | — | US | disclosed |
| EP-1838306-B1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH AS (DK) | 2010-11-17 | — | — | EP | disclosed |
| US-20100280087-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | SOERENSEN ULRIK SVANE | 2010-11-04 | — | — | US | disclosed |
| EP-1910314-B1 | BENZIMIDAZOLE DERIVATIVES FOR TREATMENT OF INFLAMMATORY DISEASES | NOVARTIS AG (CH) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009080818-A2 | GUANIDINE BASED COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2009-07-02 | — | — | WO | disclosed |
| US-20080200529-A1 | Novel 2-Amino Benzimidazole Derivatives and Their Use As Modulators Of Small-Conductance Calcium-Activated Potassium Channels | NEURO SEARCH A/S (DK) | 2008-08-21 | — | — | US | disclosed |
| WO-2008031016-A2 | HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-13 | — | — | WO | disclosed |
| US-7338956-B2 | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-03-04 | — | — | US | disclosed |
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1838306-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2007-10-03 | — | — | EP | disclosed |
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006074991-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | NEUROSEARCH A/S (DK) | 2006-07-20 | — | — | WO | disclosed |
| US-20050234083-A1 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-10-20 | — | — | US | disclosed |
| EP-1534275-A1 | ACYLAMINO-SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Aventis Pharma Deutschland GmbH (DE) | 2005-06-01 | — | — | EP | disclosed |
| EP-1487824-A1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-12-22 | — | — | EP | disclosed |
| US-20040110808-A1 | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-1417482-A2 | METHOD AND DEVICE FOR DIRECTED SORT COMBINATIONAL SYNTHESIS | High Throughput Genomics, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2004014369-A1 | ACYLAMINO-SUBSTITUTED HETEROAROMATIC COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-02-19 | — | — | WO | disclosed |
| EP-1388341-A1 | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals | Aventis Pharma Deutschland GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6660870-B1 | Serotonergic compounds which possess agonist activity at 5-HT2 receptors effectively lower and control normal and elevated IOP and are useful for treating glaucoma | ALCON, INC. (CH) | 2003-12-09 | — | — | US | disclosed |
| US-6660870-B1 | Serotonergic compounds which possess agonist activity at 5-HT2 receptors effectively lower and control normal and elevated IOP and are useful for treating glaucoma | ALCON, INC. (CH) | 2003-12-09 | — | — | US | disclosed |
| US-6660870-B1 | Serotonergic compounds which possess agonist activity at 5-HT2 receptors effectively lower and control normal and elevated IOP and are useful for treating glaucoma | ALCON, INC. (CH) | 2003-12-09 | — | — | US | disclosed |
| EP-1206265-B1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2003-11-12 | — | — | EP | disclosed |
| WO-2003074515-A1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-12 | — | — | WO | disclosed |
| WO-2003009940-A2 | METHOD AND DEVICE FOR DIRECTED SORT COMBINATIONAL SYNTHESIS | HIGH THROUGHPUT GENOMICS, INC. (US) | 2003-02-06 | — | — | WO | disclosed |
| US-6498165-B1 | PYRIMIDINE COMPOUNDS; PROPHYLAXIS AND TREATMENT OF SUCH AS IMMUNE DISEASES, HYPERPROLIFERATIVE DISORDERS, CANCER, ANGIOGENSIS, ATHEROSCELEROSIS, GRAFT REJECTION, RHEUMATOID ARTHRITIS, PSORIASIS | MERCK & CO., INC. | 2002-12-24 | — | — | US | disclosed |
| EP-1194152-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1206260-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-1206265-A4 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO INC (US) | 2002-08-07 | — | — | EP | disclosed |
| EP-1206265-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1206260-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-05-22 | — | — | EP | disclosed |
| EP-1194152-A1 | SRC KINASE INHIBITOR COMPOUNDS | Merck & Co., Inc. (US) | 2002-04-10 | — | — | EP | disclosed |
| US-6329380-B1 | PYRIMIDINE BENZIMIDIZAZOLE, PYRIMIDINEIMIDAZOLE OR PYRIDINE IMIDAZOLE COMPOUNDS FOR ANTICANCER AGENTS OR ATHEROSCLEROSIS | MERCK & CO., INC. | 2001-12-11 | — | — | US | disclosed |
| US-6316444-B1 | SRC kinase inhibitor compounds | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |
| WO-2001070705-A1 | 2-ACYLAMINOBENZIMIDAZOLE DERIVATIVES FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001070705-A1 | 2-ACYLAMINOBENZIMIDAZOLE DERIVATIVES FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001000207-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000213-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| WO-2001000214-A1 | SRC KINASE INHIBITOR COMPOUNDS | MERCK & CO., INC. (US) | 2001-01-04 | — | — | WO | disclosed |
| US-5961837-A | WATER TO BE UTILIZED IS REACTED WITH SODA ASH AND LIME TO PRODUCE A LESS CORROSIVE AND FOULANT WATER. REACTION SLUDGES ARE FED TO A DESULFURIZATION UNIT WHERE SULFUR AND NITROGEN OXIDES AND CO2 ABATEMENT OCCURS. | FERRARA MARCELLO (IT) | 1999-10-05 | — | — | US | disclosed |
| US-5683587-A | PRODUCING A SLUDGE OF CALCIUM CARBONATE AND MAGNESIUM HYDROXIDE BY REACTION OF SODA ASH WITH LIME IN WATER FEEDING WASTE GASES CONTAINING POLLLUTANTS FOR SCRUBBING, SEPARATION AND INJECTION INTO REACTION CHAMBER | FERRARA MARCELLO (IT) | 1997-11-04 | — | — | US | disclosed |
| EP-0311089-B1 | An arrangement for preventing entrance of harmful particles for use in a cartridge | HITACHI MAXELL (JP) | 1993-12-29 | — | — | EP | disclosed |
| US-4933797-A | Arrangement for preventing entrance of harmful particles for use in a cartridge | HITACHI MAXELL LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0311089-A2 | An arrangement for preventing entrance of harmful particles for use in a cartridge | Hitachi Maxell Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |
| EP-0112133-B1 | 5-PHENYLETHENYLBENZIMIDAZOLES | SMITHKLINE BECKMAN CORPORATION (US) | 1987-10-21 | — | — | EP | disclosed |
| US-4492708-A | Antiviral benzimidazoles | ELI LILLY AND COMPANY (US) | 1985-01-08 | — | — | US | disclosed |
| EP-0112133-A1 | 5-Phenylethenylbenzimidazoles | SMITHKLINE BECKMAN CORPORATION (US) | 1984-06-27 | — | — | EP | disclosed |
| EP-0111993-A2 | Improvements in or relating to benzimidazoles | ELI LILLY AND COMPANY (US) | 1984-06-27 | — | — | EP | disclosed |
| US-4435418-A | ANTHELMINTICS, 2-ACYLAMINO SUBSTITUTED | SMITHKLINE BECKMAN CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |
| US-4059584-A | ANTIINFLAMMATORY | PFIZER (US) | 1977-11-22 | — | — | US | disclosed |
| US-4011236-A | N-(BENZIMIDAZOL-2-YL)ARYLCARBOXAMIDES AS ULTRAVIOLET (UV) LIGHT ABSORBERS | MERCK & CO., INC. (US) | 1977-03-08 | — | — | US | disclosed |
| US-4002623-A | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines | PFIZER INC. (US) | 1977-01-11 | — | — | US | disclosed |
| US-4002623-A | Anti-inflammatory 1-[3-(dialkylamino)propyl]-2-acylaminobenzimidazoles and 2-acylamino-3-[3-(dialkylamino)-propyl]imidazo[4,5-b]pyridines | PFIZER INC. (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (18 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309755-A1 | NOVEL COMPOUNDS | PTGER1, PTGS1, PTGES | BCHE 1604/4885TRPC3 2869/4885TRPC4 3331/4885 |
| US-20100310455-A1 | Heterocyclic Ligands for Integrin Imaging and Therapy | ITGA1, ITGAL, ITGA4 | BCHE 4291/4885TRPC3 1281/4885TRPC4 536/4885 |
| US-20040110808-A1 | Acylamino-substituted heteroaromatic compounds and their use as pharmaceuticals | EDNRA, LIPG, CYP11B1 | BCHE 2047/4885TRPC3 2005/4885TRPC4 2590/4885 |
| US-20120309738-A1 | NOVEL COMPOUNDS | PTGER1, PTGS1, PTGES | BCHE 1442/4885TRPC3 2991/4885TRPC4 3509/4885 |
| US-20050234083-A1 | Diamino-pyrimidines and their use as angiogenesis inhibitors | TIE1, TEK, KDR | BCHE 4237/4885TRPC3 3551/4885TRPC4 3980/4885 |
| US-20170240556-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | CNKSR1, TYK2, ERBB2 | BCHE 1510/4885TRPC3 898/4885TRPC4 2551/4885 |
| US-20170087162-A1 | COMBINATION THERAPY FOR MDS | MCL1, IRAK4, IRAK3 | BCHE 4183/4885TRPC3 3017/4885TRPC4 2071/4885 |
| US-20180282734-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF HEAD AND NECK CANCER | IRAK1, IRAK4, IRAK2 | BCHE 4621/4885TRPC3 3870/4885TRPC4 4209/4885 |
| US-20110034527-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | KCNN2, KCNN1, KCNN3 | BCHE 3364/4885TRPC3 80/4885TRPC4 77/4885 |
| US-20150158878-A1 | BIFLUORODIOXALANE-AMINO-BENZIMIDAZOLE KINASE INHIBITORS FOR THE TREATMENT OF CANCER, AUTOIMMUNEINFLAMMATION AND CNS DISORDERS | CHUK, KYNU, BLK | BCHE 1912/4885TRPC3 1161/4885TRPC4 2823/4885 |
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | BCHE 1543/4885TRPC3 2975/4885TRPC4 3368/4885 |
| US-20160038529-A1 | COMBINATION THERAPY FOR MDS | MCL1, IRAK4, IRAK3 | BCHE 4183/4885TRPC3 3017/4885TRPC4 2071/4885 |
| US-20080200529-A1 | Novel 2-Amino Benzimidazole Derivatives and Their Use As Modulators Of Small-Conductance Calcium-Activated Potassium Channels | KCNN2, KCNN1, KCNN3 | BCHE 3364/4885TRPC3 80/4885TRPC4 77/4885 |
| US-20100331384-A1 | GUANIDINE BASED COMPOUNDS | ADRB2, ADRA2A, ADRA2C | BCHE 1702/4885TRPC3 667/4885TRPC4 632/4885 |
| US-20120214786-A1 | NEW COMPOUNDS | PTGER1, PTGS1, PTGES | BCHE 1513/4885TRPC3 2614/4885TRPC4 2981/4885 |
| US-20100280087-A1 | NOVEL 2-AMINO BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS MODULATORS OF SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS | KCNN2, KCNN1, KCNN3 | BCHE 3364/4885TRPC3 80/4885TRPC4 77/4885 |
| US-20140350070-A1 | Combination Therapy for MDS | MCL1, IRAK4, IRAK3 | BCHE 4183/4885TRPC3 3017/4885TRPC4 2071/4885 |
| US-20120208839-A1 | NEW COMPOUNDS | PTGER1, PTGS1, PTGES | BCHE 1633/4885TRPC3 2385/4885TRPC4 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.