Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexaflumuron SCHEMBL26793 | 0.93 | MEN1 (0.59) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10885396 | 0.92 | MEN1 (0.55) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL7586417 | 0.91 | MEN1 (0.68) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL7585705 | 0.90 | MEN1 (0.56) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9775648 | 0.89 | KMT2A (0.49) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL7619998 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL10496460 | 0.88 | MEN1 (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| Hexaflumuron SCHEMBL17607272 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659704 | 0.87 | MEN1 (0.63) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9804080 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896532-B1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2002-10-02 | — | — | EP | claimed |
| EP-0896532-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | Novartis AG (CH) | 1999-02-17 | — | — | EP | claimed |
| US-5837734-A | Method for the treatment of coccidioidomycosis in warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-11-17 | — | — | US | claimed |
| WO-1997040826-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | claimed |
| US-5416102-A | Administering orally, by injection or implantation, a dosage of flea growth inhibiting benzoyl urea compound | CIBA-GEIGY CORPORATION (US) | 1995-05-16 | — | — | US | claimed |
| EP-0896532-B1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 2002-10-02 | — | — | EP | disclosed |
| EP-0896532-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | Novartis AG (CH) | 1999-02-17 | — | — | EP | disclosed |
| US-5837734-A | Method for the treatment of coccidioidomycosis in warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1997040826-A1 | ACYL UREA COMPOUNDS FOR THE TREATMENT OF COCCIDIOIDOMYCOSIS IN WARM-BLOODED ANIMALS | NOVARTIS AG (CH) | 1997-11-06 | — | — | WO | disclosed |
| US-5416102-A | Administering orally, by injection or implantation, a dosage of flea growth inhibiting benzoyl urea compound | CIBA-GEIGY CORPORATION (US) | 1995-05-16 | — | — | US | disclosed |
| US-4536341-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1985-08-20 | — | — | US | disclosed |
| US-4468405-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1984-08-28 | — | — | US | disclosed |