Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586547 | 0.89 | MEN1 (0.57) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10496460 | 0.88 | MEN1 (0.51) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Hexaflumuron SCHEMBL26793 | 0.82 | MEN1 (0.59) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL11026869 | 0.82 | MEN1 (0.53) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10885396 | 0.81 | MEN1 (0.55) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL7586417 | 0.80 | MEN1 (0.68) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL10615828 | 0.80 | MEN1 (0.50) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL9775594 | 0.80 | MEN1 (0.51) | KMT2AMEN1MAPTUSP2ALOX15 | |
| SCHEMBL7585705 | 0.79 | MEN1 (0.56) | KMT2AMEN1MAPTUSP2ALOX15 | |
| Hexaflumuron SCHEMBL17607272 | 0.79 | MEN1 (0.53) | KMT2AMEN1MAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001266-A | Substituted aniline compounds | THE DOW CHEMICAL COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| US-4868215-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| EP-0071279-B1 | SUBSTITUTED N-AROYL N'-PHENYL UREA COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1986-09-03 | — | — | EP | disclosed |
| EP-0071279-A1 | Substituted N-aroyl N'-phenyl urea compounds | THE DOW CHEMICAL COMPANY (US) | 1983-02-09 | — | — | EP | disclosed |