Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854206 | 1.00 | ESR1 (0.38) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL7589126 | 0.92 | ESR1 (0.35) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5854590 | 0.91 | ESR1 (0.40) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5854650 | 0.89 | ESR1 (0.33) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5856161 | 0.89 | ESR1 (0.33) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5854267 | 0.88 | ESR1 (0.34) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5857359 | 0.85 | PPARD (0.33) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5854218 | 0.83 | PTPN1 (0.33) | FFAR1PPARGPPARDMMP2MMP3 | |
| SCHEMBL5854239 | 0.81 | ALDH1A1 (0.34) | ESR1ESR2FFAR1PPARGPPARD | |
| SCHEMBL5854269 | 0.81 | PTPN1 (0.35) | FFAR1PPARGPPARDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| US-6153768-A | RECEPTOR BLOCKING ANTIESTROGENS HAVING REDUCED SIDE EFFECTS | C & C RESEARCH LABORATORIES (KR) | 2000-11-28 | — | — | US | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |