Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.62 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.62 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7384232 | 0.95 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL7651159 | 0.95 | ITGB1 (0.64) | ITGB1ITGA4 | |
| SCHEMBL7426550 | 0.91 | ITGA4 (0.64) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7423658 | 0.91 | ITGB1 (0.65) | ITGB1ITGA4 | |
| SCHEMBL7382674 | 0.90 | ITGB1 (0.64) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7651606 | 0.89 | ITGB1 (0.58) | ITGB1ITGA4 | |
| SCHEMBL5700893 | 0.89 | ITGB1 (0.73) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5700889 | 0.89 | ITGB1 (0.73) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7483837 | 0.88 | ITGB1 (0.59) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7384591 | 0.88 | ITGA4 (0.61) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |
| EP-1027328-A1 | SUBSTITUTED ANILIDES | Aventis Pharma Limited (GB) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999023063-A1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LIMITED (GB) | 1999-05-14 | — | — | WO | disclosed |