Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585086 | 0.92 | CA2 (0.38) | SPHK1OPRM1CYP2D6LMNATP53 | |
| Bromide SCHEMBL8678418 | 0.86 | TSHR (0.48) | SPHK1CYP2D6LMNATP53GMNN | |
| SCHEMBL10944404 | 0.83 | SPHK1 (0.50) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL10944400 | 0.83 | SPHK1 (0.50) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL5671085 | 0.83 | SPHK1 (0.50) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL4008504 | 0.83 | SPHK1 (0.50) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL5053889 | 0.81 | TSHR (0.35) | SPHK1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL5053423 | 0.81 | SPHK1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL9575906 | 0.81 | SPHK1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 | |
| SCHEMBL9575712 | 0.81 | SPHK1 (0.48) | SPHK1OPRM1CYP2D6LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1245249-A2 | Use of a cationic amphipathic compound as a transfection agent, vaccine additive or drug | Aventis Pasteur (FR) | 2002-10-02 | — | — | EP | disclosed |
| EP-0769942-A1 | USE OF A CATIONIC AMPHIPATHIC COMPOUND AS A TRANSFECTION AGENT, VACCINE ADDITIVE OR DRUG | PASTEUR MERIEUX SERUMS ET VACCINS (FR) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996032102-A1 | USE OF A CATIONIC AMPHIPATHIC COMPOUND AS A TRANSFECTION AGENT, VACCINE ADDITIVE OR DRUG | PASTEUR MERIEUX SERUMS ET VACCINS (FR) | 1996-10-17 | — | — | WO | disclosed |