Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.49 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.42 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.42 |
| ▸ | GAK | O14976 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574942 | 0.97 | EGFR (0.51) | EGFRCSNK2A1CSNK2A2CSNK2BERBB2 | |
| SCHEMBL7585627 | 0.94 | CSNK2A1 (0.47) | EGFRCSNK2A1CSNK2A2CSNK2BERBB2 | |
| SCHEMBL7576275 | 0.90 | EGFR (0.52) | EGFRERBB2HPGDHTTBRAF | |
| SCHEMBL7576103 | 0.89 | EGFR (0.53) | EGFRERBB2HPGDHTTBRAF | |
| SCHEMBL7588582 | 0.89 | EGFR (0.54) | EGFRCSNK2A1CSNK2A2CSNK2BERBB2 | |
| SCHEMBL7588633 | 0.86 | EGFR (0.55) | EGFRERBB2HPGDHTTBRAF | |
| SCHEMBL7582363 | 0.86 | EGFR (0.52) | EGFRERBB2BRAFERBB3ERBB4 | |
| SCHEMBL7578264 | 0.86 | EGFR (0.57) | EGFRCSNK2A1CSNK2A2CSNK2BERBB2 | |
| SCHEMBL7575509 | 0.86 | EGFR (0.56) | EGFRERBB2HPGDHTTBRAF | |
| SCHEMBL7583456 | 0.85 | EGFR (0.48) | EGFRCSNK2A1CSNK2A2CSNK2BERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | PKD1, REN, CYP11B1 | EGFR 1041/4885CSNK2A1 525/4885CSNK2A2 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.