Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275289 | 1.00 | SRC (0.49) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL10783437 | 0.86 | SRC (0.47) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8679670 | 0.83 | SRC (0.53) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL7944663 | 0.83 | SRC (0.53) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL6888225 | 0.83 | SRC (0.53) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL3675107 | 0.82 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL3675110 | 0.82 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL20522377 | 0.82 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL31281022 | 0.82 | SRC (0.52) | SRCKDM4EALDH1A1HPGDGAA | |
| SCHEMBL20876123 | 0.79 | SRC (0.48) | SRCKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235927-A2 | NOVEL ENZYMATIC SUBSTRATES FOR DETECTING PSEUDOMONAS AERUGINOSA | Biomerieux S.A. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001042491-A2 | NOVEL ENZYMATIC SUBSTRATES FOR DETECTING PSEUDOMONAS AERUGINOSA | BIOMERIEUX S.A. (FR) | 2001-06-14 | — | — | WO | disclosed |
| EP-0516814-B1 | METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS | DADE MICROSCAN INC (US) | 1996-09-04 | — | — | EP | disclosed |
| US-5457030-A | Using fluorogenic substrates to detect bacterial growth | MICROSCAN, INC. (US) | 1995-10-10 | — | — | US | disclosed |
| EP-0516814-A4 | METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS | BAXTER DIAGNOSTICS INC (US) | 1994-06-01 | — | — | EP | disclosed |
| EP-0516814-A1 | METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS. | BAXTER DIAGNOSTICS INC (US) | 1992-12-09 | — | — | EP | disclosed |
| WO-1992012257-A1 | METHOD AND COMPOSITION FOR DETERMINING ANTIMICROBIAL SUSCEPTIBILITY OF THE MAJORITY OF CLINICALLY SIGNIFICANT GRAM POSITIVE ORGANISMS | BAXTER DIAGNOSTICS INC. (US) | 1992-07-23 | — | — | WO | disclosed |