SCHEMBL3675110

SCHEMBL3675110

Cc1c(C(=O)[C@@H](N)CCC(N)=O)c(=O)oc2cc(N)ccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.46
KDM4E B2RXH2 7/20 0.40
ALDH1A1 P00352 7/20 0.40
HPGD P15428 6/20 0.40
HSD17B10 Q99714 4/20 0.40
GLA P06280 3/20 0.40
GAA P10253 3/20 0.40
CASP1 P29466 3/20 0.40
CASP7 P55210 3/20 0.40
TSHR P16473 1/20 0.40
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
HSD17B3 P37058 4/20 0.37
MAPT P10636 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HIF1A Q16665 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ACHE P22303 1/20 0.37
PKM P14618 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20522377 1.00 SRC (0.46) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3675107 0.91 SRC (0.46) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL10783437 0.84 SRC (0.47) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL10779017 0.82 SRC (0.43) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL15101764 0.82 SRC (0.46) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3201776 0.82 SRC (0.46) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL7586984 0.82 SRC (0.49) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL3275289 0.82 SRC (0.49) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6888225 0.79 SRC (0.53) SRCKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8679670 0.76 SRC (0.53) SRCKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2167678-A2 A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED Universita' Di Pisa (IT) 2010-03-31 EP claimed
WO-2009001290-A2 A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED UNIVERSITA' DI PISA (IT) 2008-12-31 WO claimed
EP-2167678-A2 A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED Universita' Di Pisa (IT) 2010-03-31 EP disclosed
WO-2009001290-A2 A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED UNIVERSITA' DI PISA (IT) 2008-12-31 WO disclosed