Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18832098 | 0.83 | LPAR3 (0.37) | LPAR3LPAR2TYMSPPARDALDH1A1 | |
| SCHEMBL402749 | 0.80 | LPAR3 (0.38) | LPAR3LPAR2TYMSPPARDALDH1A1 | |
| SCHEMBL1060704 | 0.75 | — | — | |
| SCHEMBL20875719 | 0.75 | LPAR3 (0.43) | LPAR3LPAR2TYMSALDH1A1TDP1 | |
| SCHEMBL7021919 | 0.72 | LPAR3 (0.45) | LPAR3LPAR2TYMSALDH1A1TDP1 | |
| Diethylamine SCHEMBL27846392 | 0.72 | S1PR2 (0.34) | LPAR3LPAR2TYMSPPARDS1PR2 | |
| SCHEMBL16268290 | 0.71 | GRM4 (0.34) | LPAR3LPAR2GRM4 | |
| SCHEMBL20875716 | 0.71 | LPAR3 (0.48) | LPAR3LPAR2TYMSALDH1A1TDP1 | |
| SCHEMBL3790944 | 0.71 | — | — | |
| SCHEMBL22370095 | 0.69 | LPAR3 (0.52) | LPAR3LPAR2TYMSALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197986-B1 | PHOSPHATO- OR PHOSPHONOALKYLSILANEDIOLS, TRIOLS; DRUGS, COSMETICS | EXSYMOL S.A.M. (FR) | 2001-03-06 | — | — | US | claimed |
| JP-10279467-A | — | — | None | — | — | JP | disclosed |
| EP-0867445-B1 | Complexes based on biologically silicon in solid form. | EXSYMOL SA (MC) | 2002-10-09 | — | — | EP | disclosed |
| US-6197986-B1 | PHOSPHATO- OR PHOSPHONOALKYLSILANEDIOLS, TRIOLS; DRUGS, COSMETICS | EXSYMOL S.A.M. (FR) | 2001-03-06 | — | — | US | disclosed |
| JP-H10279467-A | SOLID AND BIOLOGICALLY ACTIVE SILICON-CONTAINING COMPOUND | EXSYMOL SAM | 1998-10-20 | — | — | JP | disclosed |
| EP-0867445-A1 | Compounds based on biologically active silicon in solid form | EXSYMOL S.A.M. (MC) | 1998-09-30 | — | — | EP | disclosed |