Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 17/20 | 0.39 |
| ▸ | THRA | P10827 | 15/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7249537 | 0.88 | NR3C1 (0.70) | NR3C1THRBTHRA | |
| SCHEMBL7250938 | 0.88 | NR3C1 (0.57) | NR3C1THRBTHRAALOX15TSHR | |
| SCHEMBL7549354 | 0.86 | NR3C1 (0.50) | NR3C1THRBTHRANR1H4 | |
| SCHEMBL7549755 | 0.86 | NR3C1 (0.50) | NR3C1THRBTHRANR1H4 | |
| SCHEMBL7577562 | 0.85 | NR3C1 (0.49) | NR3C1THRBTHRANR1H4 | |
| SCHEMBL7549161 | 0.85 | NR3C1 (0.49) | NR3C1THRBTHRA | |
| SCHEMBL7250975 | 0.85 | NR3C1 (0.54) | NR3C1THRBTHRA | |
| SCHEMBL7553498 | 0.83 | NR3C1 (0.52) | NR3C1THRBTHRA | |
| SCHEMBL7255589 | 0.83 | NR3C1 (0.57) | NR3C1THRBTHRA | |
| SCHEMBL7250343 | 0.82 | NR3C1 (0.57) | NR3C1THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002044120-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III | KARO BIO AB (SE) | 2002-06-06 | — | — | WO | disclosed |