SCHEMBL7587362

SCHEMBL7587362

CC(C)(OC(=O)N1CCN(C(Cc2ccc(C#N)cc2)c2cnc[nH]2)CC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 4/20 0.38
P2RX7 Q99572 1/20 0.34
PGGT1B P53609 8/20 0.34
FNTA P49354 7/20 0.34
FNTB P49356 7/20 0.34
HRH3 Q9Y5N1 2/20 0.33
DPP4 P27487 1/20 0.33
FAP Q12884 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
PRKAA2 P54646 1/20 0.33
CHRM3 P20309 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128883 0.85 HRH3 (0.34) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7593385 0.83 FNTA (0.38) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7130693 0.81 DPP4 (0.38) HRH3DPP4FAPDPP8DPP9
SCHEMBL7593432 0.81 FNTA (0.36) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7128886 0.81 FNTA (0.36) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7593498 0.81 FNTA (0.36) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7118951 0.81 FNTA (0.36) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7127275 0.81 FNTA (0.36) GPR119PGGT1BFNTAFNTBHRH3
SCHEMBL7592792 0.81 HRH1 (0.41) GPR119P2RX7PGGT1BFNTAFNTB
SCHEMBL7716788 0.80 DPP4 (0.36) HRH3DPP4FAPDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020072081-A1 Geranylgeranyl transferase inhibitor screening assay ENG WAI-SI (US) 2002-06-13 US claimed
US-20020072081-A1 Geranylgeranyl transferase inhibitor screening assay ENG WAI-SI (US) 2002-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072081-A1 Geranylgeranyl transferase inhibitor screening assay GGT1, FNTA, GGPS1 GPR119 2391/4885P2RX7 4688/4885PGGT1B 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.