Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL20590969 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL3741817 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9188682 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL15588 | 0.82 | — | — | |
| Ammonia Solution, Strong SCHEMBL23930398 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL20718913 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL5873257 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL20496416 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL817608 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL8651565 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 428 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220145346-A1 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | CAMENA BIOSCIENCE LIMITED (GB) | 2022-05-12 | — | — | US | claimed |
| EP-3911757-A2 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | Camena Bioscience Limited (GB) | 2021-11-24 | — | — | EP | claimed |
| US-20210087600-A1 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | CAMENA BIOSCIENCE LIMITED (GB) | 2021-03-25 | — | — | US | claimed |
| EP-3737755-A1 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | Camena Bioscience Limited (GB) | 2020-11-18 | — | — | EP | claimed |
| WO-2020150143-A2 | COMPOSITIONS AND METHODS FOR TEMPLATE-FREE GEOMETRIC ENZYMATIC NUCLEIC ACID SYNTHESIS | CAMENA BIOSCIENCE LIMITED (GB) | 2020-07-23 | — | — | WO | claimed |
| WO-2017218925-A1 | MODIFIED 3' REGION EXTRACTION AND DEEP SEQUENCING OF POLYADENYLATION SITES AND POLY(A) TAIL LENGTH ANALYSIS | RUTGENTS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-12-21 | — | — | WO | claimed |
| US-20170267998-A1 | METHODS OF SYNTHESIZING POLYNUCLEOTIDES | AXIOMX, INC. | 2017-09-21 | — | — | US | claimed |
| US-20120309952-A1 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2012-12-06 | — | — | US | claimed |
| EP-1996730-A2 | SMALL RNA PURIFICATION | PROMEGA CORPORATION (US) | 2008-12-03 | — | — | EP | claimed |
| US-20080139800-A1 | Process For the Concentration and/or Isolation of Nucleic Acid or Nucleic Acid-Containing Species | QIAGEN GMBH (DE) | 2008-06-12 | — | — | US | claimed |
| EP-0728211-B1 | PROCESS OF PRODUCING HIGHLY TRANSFORMABLE BACTERIAL CELLS AND CELLS PRODUCED THEREBY | STRATAGENE INC (US) | 2001-05-16 | — | — | EP | claimed |
| EP-1005527-A1 | HIGHLY TRANSFORMABLE BACTERIAL CELLS AND METHODS FOR PRODUCING THE SAME | STRATAGENE (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998049266-A1 | HIGHLY TRANSFORMABLE BACTERIAL CELLS AND METHODS FOR PRODUCING THE SAME | STRATAGENE (US) | 1998-11-05 | — | — | WO | claimed |
| US-5707841-A | Process of producing highly transformable bacterial cells and cells produced thereby | STRATAGENE (US) | 1998-01-13 | — | — | US | claimed |
| EP-0728211-A1 | PROCESS OF PRODUCING HIGHLY TRANSFORMABLE BACTERIAL CELLS AND CELLS PRODUCED THEREBY | STRATAGENE (US) | 1996-08-28 | — | — | EP | claimed |
| US-5512468-A | TRANSFERRING A GENE ENCODING AN ENZYME WITH CARBOHYDRATE DEGRADING ACTIVITY INTO E. COLI CELLS AND SUBSEQUENTLY RENDERING THE CELLS COMPETENT | STRATAGENE (US) | 1996-04-30 | — | — | US | claimed |
| WO-1995013388-A1 | PROCESS OF PRODUCING HIGHLY TRANSFORMABLE BACTERIAL CELLS AND CELLS PRODUCED THEREBY | STRATAGENE (US) | 1995-05-18 | — | — | WO | claimed |
| EP-0212444-B1 | PROCESS OF PRODUCING HIGHLY TRANSFORMABLE CELLS AND CELLS PRODUCED THEREBY | LIFE TECHNOLOGIES INC. (US) | 1992-03-25 | — | — | EP | claimed |
| US-4981797-A | ESCHERICHIA FOR GENETIC ENGINEERING | LIFE TECHNOLOGIES, INC. (US) | 1991-01-01 | — | — | US | claimed |
| EP-0212444-A2 | Process of producing highly transformable cells and cells produced thereby | LIFE TECHNOLOGIES INC. (US) | 1987-03-04 | — | — | EP | claimed |