Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL225938 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL2732387 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL14120418 | 0.75 | PLAU (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL24214452 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL6448469 | 0.75 | NISCH (0.49) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL25082548 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL10754929 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL18286810 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL14395682 | 0.75 | NISCH (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB | |
| SCHEMBL29433047 | 0.75 | PLAU (0.45) | NISCHSIGMAR1HTR1AOXTRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6368573-B1 | MEASURING MYOCARDIAL FUNCTION IN MAMMAL | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2002-04-09 | — | — | US | disclosed |
| EP-0323807-A2 | Certain 2-substituted adenosine derivatives | CIBA-GEIGY AG (CH) | 1989-07-12 | — | — | EP | disclosed |