Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AOC2 | O75106 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440596 | 1.00 | NISCH (0.45) | NISCHSIGMAR1MAOBTP53HTR1A | |
| SCHEMBL14395682 | 1.00 | NISCH (0.45) | NISCHSIGMAR1MAOBTP53HTR1A | |
| SCHEMBL25082548 | 1.00 | NISCH (0.45) | NISCHSIGMAR1MAOBTP53HTR1A | |
| Water SCHEMBL27491170 | 0.98 | NISCH (0.44) | NISCHSIGMAR1MAOBTP53HTR1A | |
| SCHEMBL2832695 | 0.80 | ABCG2 (0.57) | NISCHMAOBHTR1AMAOA | |
| SCHEMBL18100543 | 0.80 | ABCG2 (0.57) | NISCHMAOBHTR1AMAOA | |
| SCHEMBL18100548 | 0.80 | ABCG2 (0.57) | NISCHMAOBHTR1AMAOA | |
| Methane SCHEMBL8607471 | 0.79 | MAP3K14 (0.42) | NISCHSIGMAR1MAOBHTR1AOXTR | |
| SCHEMBL23558482 | 0.77 | LTB4R (0.40) | — | |
| SCHEMBL10754929 | 0.75 | NISCH (0.45) | NISCHSIGMAR1MAOBTP53HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183431-A | One kind is for liver disease or the compound of prevention | 江苏新元素医药科技有限公司 | 2019-08-30 | — | — | CN | claimed |
| US-20170260152-A1 | 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-09-14 | — | — | US | claimed |
| EP-3186235-A2 | 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING | SABIC Global Technologies B.V. (NL) | 2017-07-05 | — | — | EP | claimed |
| CN-106660978-A | 2-(2,3-epoxypropyl)phenol composition and method of making | 沙特基础工业全球技术有限公司 | 2017-05-10 | — | — | CN | claimed |
| WO-2016032997-A2 | 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-03-03 | — | — | WO | claimed |
| US-5071991-A | METHOD OF PREPARING CHROMAN DERIVATIVES, AND SYNTHESIS INTERMEDIATES | SANOFI (FR) | 1991-12-10 | — | — | US | claimed |
| JP-59029682-A | — | — | None | — | — | JP | disclosed |
| CN-118005595-B | Synthesis and antitumor activity of chroman derivatives having allyl alcohol structure | 内蒙古大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118005594-B | Synthesis of 3-hydroxybenzodihydropyran derivative and antitumor activity thereof | 内蒙古大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-118005677-A | Method for asymmetrically synthesizing chroman with three-level silyl ether structure by nickel catalysis | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005680-A | Synthesis method of chiral chroman with allyl silyl ether structure | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005682-A | Asymmetric synthesis method of chroman derivative with allyl silyl ether structure | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005679-A | Method for enantioselectively synthesizing chromane with allyl silyl ether structure | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| EP-0470176-A1 | SUBSTITUTED 3-AMINO CHROMANS. | UPJOHN CO (US) | 1992-02-12 | — | — | EP | disclosed |
| US-5013853-A | Chroman derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-05-07 | — | — | US | disclosed |
| CN-1043319-A | New amine and uses thereof | MITSUI PHARMACEUTICALS (JP) | 1990-06-27 | — | — | CN | disclosed |
| EP-0120428-B1 | BENZOPYRAN ISOMERS | BEECHAM GROUP PLC (GB) | 1990-05-23 | — | — | EP | disclosed |
| EP-0346724-A1 | Chroman derivates | MERCK PATENT GmbH (DE) | 1989-12-20 | — | — | EP | disclosed |
| EP-0120428-A1 | Benzopyran isomers | BEECHAM GROUP PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| JP-S5929682-A | PREPARATION OF 3,4-DIHYDRO-2H-1-BENZOPYRAN-3-OL DERIVATIVE | KOWA CO | 1984-02-16 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170260152-A1 | 2-(2,3-EPOXYPROPYL)PHENOL COMPOSITION AND METHOD OF MAKING | CYP2J2, HMOX2, PRDX2 | NISCH 2159/4885SIGMAR1 2530/4885MAOB 476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.