SCHEMBL7587737

SCHEMBL7587737

C/C=C\[C@@H]1[C@@H](C(=O)OCc2c(F)c(F)c(C)c(F)c2F)C1(C)C

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.67
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ADRA2A P08913 1/20 0.34
CNR1 P21554 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TSHR P16473 1/20 0.33
IMPDH2 P12268 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7926862 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1920258 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL26958 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL132969 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29365307 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL7522431 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1920260 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1920262 1.00 TDP1 (0.67) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL29843023 0.95 TDP1 (0.61) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL21959829 0.94 TDP1 (0.58) TDP1MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939073-B1 Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides SUMITOMO CHEMICAL CO (JP) 2002-12-04 EP claimed
US-6225495-B1 PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-01 US claimed
EP-2670246-B1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL CO (JP) 2017-10-04 EP disclosed
US-20130303610-A1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-11-14 US disclosed
US-6225495-B1 PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130303610-A1 PESTICIDAL COMPOSITION AND METHOD FOR CONTROLLING PESTS DDT, SGMS1, ACHE TDP1 2913/4885MEN1 1212/4885KMT2A 90/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.