SCHEMBL7588375

SCHEMBL7588375

CC(COC(=O)C=Cc1ccco1)OC(=O)C=Cc1ccco1

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 10/20 0.62
CACNA1B Q00975 2/20 0.62
APBA1 Q02410 2/20 0.62
TDP1 Q9NUW8 14/20 0.59
L3MBTL1 Q9Y468 6/20 0.59
ALDH1A1 P00352 5/20 0.59
APEX1 P27695 3/20 0.52
CTDSP1 Q9GZU7 3/20 0.51
RECQL P46063 2/20 0.51
APOBEC3A P31941 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
MEN1 O00255 1/20 0.51
BLM P54132 1/20 0.51
KMT2A Q03164 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
PKM P14618 1/20 0.51
HCAR2 Q8TDS4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7588372 1.00 POLB (0.62) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL30567945 0.95 POLB (0.57) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7137634 0.94 POLB (0.56) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7137630 0.94 POLB (0.56) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7140006 0.87 POLB (0.59) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7140012 0.87 POLB (0.59) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7138121 0.84 POLB (0.60) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL7138125 0.84 POLB (0.60) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL23175323 0.83 POLB (0.59) POLBCACNA1BAPBA1TDP1L3MBTL1
SCHEMBL336288 0.83 POLB (0.59) POLBCACNA1BAPBA1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020137881-A1 Esters of 3-(2-furyl)-2propenoic acid with diols BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2002-09-26 US claimed