Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 13/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138125 | 1.00 | POLB (0.60) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL336288 | 0.92 | POLB (0.59) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL23175323 | 0.92 | POLB (0.59) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL7588375 | 0.84 | POLB (0.62) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL7588372 | 0.84 | POLB (0.62) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL1286936 | 0.83 | POLB (0.67) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL1286940 | 0.83 | POLB (0.67) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL7141083 | 0.82 | HCAR2 (0.67) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL7141082 | 0.82 | HCAR2 (0.67) | POLBCACNA1BAPBA1HCAR2TDP1 | |
| SCHEMBL7140012 | 0.82 | POLB (0.59) | POLBCACNA1BAPBA1HCAR2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506863-B2 | Used as crosslinking agents for olefin polymers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-01-14 | — | — | US | claimed |
| US-20020137881-A1 | Esters of 3-(2-furyl)-2propenoic acid with diols | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2002-09-26 | — | — | US | claimed |
| EP-1216999-A1 | Esters of the 3-(2-furyl)-2-propenoic acid with diols | Basell Poliolefine Italia S.p.A. (IT) | 2002-06-26 | — | — | EP | claimed |
| US-6506863-B2 | Used as crosslinking agents for olefin polymers | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2003-01-14 | — | — | US | disclosed |
| US-20020137881-A1 | Esters of 3-(2-furyl)-2propenoic acid with diols | BASELL POLIOLEFINE ITALIA S.P.A. (IT) | 2002-09-26 | — | — | US | disclosed |
| EP-1216999-A1 | Esters of the 3-(2-furyl)-2-propenoic acid with diols | Basell Poliolefine Italia S.p.A. (IT) | 2002-06-26 | — | — | EP | disclosed |