Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.62 |
| ▸ | PDE5A | O76074 | 3/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | PDE1A | P54750 | 1/20 | 0.52 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.52 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568142 | 0.86 | PDE4D (0.64) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL6818677 | 0.80 | PDE4D (0.61) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL7425106 | 0.77 | PDE4A (0.61) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL7422814 | 0.77 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL6819117 | 0.77 | PDE4D (0.62) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL7340175 | 0.77 | PDE4D (1.00) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL201172 | 0.76 | PDE4D (0.84) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL7423857 | 0.76 | PDE4D (0.82) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL7424332 | 0.74 | PDE4D (0.60) | PDE4APDE4DPDE4BPDE4CPDE5A | |
| SCHEMBL7450727 | 0.74 | PDE4D (1.00) | PDE4APDE4DPDE4BPDE4CPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | disclosed |