Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 15/20 | 0.60 |
| ▸ | PDE4A | P27815 | 13/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PDE5A | O76074 | 2/20 | 0.54 |
| ▸ | PDE1A | P54750 | 1/20 | 0.54 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512973 | 0.87 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7422814 | 0.86 | PDE4A (0.59) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL8323597 | 0.81 | PDE4A (0.66) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7424626 | 0.81 | PDE4A (0.66) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7450501 | 0.79 | PDE4D (0.75) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7423009 | 0.79 | PDE4D (0.76) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL202816 | 0.78 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL7568142 | 0.78 | PDE4D (0.64) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL6818669 | 0.77 | PDE4D (0.57) | PDE4DPDE4APDE4BPDE4CEPHX2 | |
| SCHEMBL12308201 | 0.76 | CYP26A1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | claimed |
| WO-1998056756-A1 | CATECHOL AMINO ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CHEIL JEDANG CORPORATION (KR) | 1998-12-17 | — | — | WO | disclosed |