Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569198 | 0.95 | CCR9 (0.44) | GSK3BPTGES2ALDH1A1SMN1; SMN2CCR9 | |
| SCHEMBL7584723 | 0.82 | PTPN2 (0.41) | GSK3BPTGES2ALDH1A1SMN1; SMN2CCR9 | |
| SCHEMBL7565871 | 0.81 | GSK3B (0.46) | GSK3BALDH1A1CCR9PTPN2PTPN1 | |
| SCHEMBL7572678 | 0.80 | GSK3B (0.42) | GSK3BPTGES2CCR9PTPN2PTPN1 | |
| SCHEMBL7590087 | 0.79 | GSK3B (0.44) | GSK3BALDH1A1CCR9PTPN2PTPN1 | |
| SCHEMBL7572797 | 0.79 | ACLY (0.49) | GSK3BACLYCCR9PTPN2PTPN1 | |
| SCHEMBL7607342 | 0.79 | CCR9 (0.43) | GSK3BPTGES2CCR9PTPN2PTPN1 | |
| SCHEMBL7593138 | 0.79 | PTGES2 (0.56) | ACLYPTGES2ALDH1A1NFKBIARELA | |
| SCHEMBL7567130 | 0.78 | GSK3B (0.45) | GSK3BALDH1A1SMN1; SMN2CCR9PTPN2 | |
| SCHEMBL7588736 | 0.78 | CCR9 (0.45) | GSK3BALDH1A1CCR9PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083629-A1 | BISSULFONAMIDE DERIVATIVES AS INHIBITORS OF DEHYDROQUINATE SYNTHETASES AND TYPE II DEHYDROQUINASES | ARROW THERAPEUTICS LIMITED (GB) | 2002-10-24 | — | — | WO | disclosed |