Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7194346 | 0.79 | HTR2A (0.36) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL1452870 | 0.76 | HTR2A (0.42) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL1453437 | 0.76 | HTR2A (0.42) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7587142 | 0.75 | PDCD1 (0.33) | — | |
| SCHEMBL4005225 | 0.74 | HTR2A (0.41) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL6238627 | 0.74 | HTR2A (0.41) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL8679551 | 0.73 | HTR2A (0.39) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7105374 | 0.73 | HTR2A (0.47) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7586039 | 0.72 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL7583845 | 0.72 | HTR2A (0.31) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115730-B1 | CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES | ALBEMARLE CORP (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1115730-A1 | CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES | ALBEMARLE CORPORATION (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017213-A1 | CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |
| US-5965759-A | Catalytic process for isomerizing metallocenes | ALBEMARLE CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |