SCHEMBL7587142

SCHEMBL7587142

CC1=Cc2c(-c3ccccc3)cccc2C1C[SiH](CC1C(C)=Cc2c(-c3ccccc3)cccc21)[Zr](Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22567806 0.83 PDCD1 (0.34) PDCD1CD274
SCHEMBL7586039 0.83 MEN1 (0.31)
SCHEMBL7583895 0.83 PDCD1 (0.32) PDCD1CD274
SCHEMBL5084813 0.81 PDCD1 (0.39) PDCD1CD274
SCHEMBL4623138 0.81 PDCD1 (0.39) PDCD1CD274
SCHEMBL28884836 0.80
SCHEMBL28884804 0.80 KDM4E (0.31)
SCHEMBL7110286 0.80 PDCD1 (0.38) PDCD1CD274
SCHEMBL6890691 0.80 PDCD1 (0.38) PDCD1CD274
SCHEMBL3998331 0.80 PDCD1 (0.38) PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330298-B1 METHOD FOR PREPARING LONG FIBER-REINFORCING OLEFIN POLYMER LG CHEMICAL LTD (KR) 2023-11-22 EP disclosed
EP-3034523-B1 METHOD FOR PREPARING PROPYLENE-1-BUTENE COPOLYMER LG CHEMICAL LTD (KR) 2021-07-07 EP disclosed
EP-3421506-B1 METALLOCENE SUPPORTED CATALYST AND METHOD FOR PRODUCING POLYPROPYLENE USING SAME LG CHEMICAL LTD (KR) 2020-12-02 EP disclosed
US-10633467-B2 Method for preparing long fiber-reinforcing olefin polymer and long fiber LG CHEM, LTD. (KR) 2020-04-28 US disclosed
US-20190106516-A1 Metallocene Supported Catalyst And Method For Preparing Polypropylene Using The Same LG CHEM, LTD. (KR) 2019-04-11 US disclosed
EP-3421506-A1 METALLOCENE SUPPORTED CATALYST AND METHOD FOR PRODUCING POLYPROPYLENE USING SAME LG Chem, Ltd. (KR) 2019-01-02 EP disclosed
EP-3330298-A1 METHOD FOR PREPARING LONG FIBER-REINFORCING OLEFIN POLYMER AND LONG FIBER LG Chem, Ltd. (KR) 2018-06-06 EP disclosed
US-9771441-B2 Preparation method of a polypropylene and a polypropylene obtained therefrom LG CHEM, LTD. (KR) 2017-09-26 US disclosed
US-9631034-B2 Non-supported heterogeneous polyolefin polymerization catalyst composition and method for preparing same LG CHEM, LTD. (KR) 2017-04-25 US disclosed
US-9587053-B2 Preparation method of a propylene-1-butene copolymer and a propylene-1-butene copolymer obtained therefrom LG CHEM, LTD. (KR) 2017-03-07 US disclosed
US-20160208028-A1 A PREPARATION METHOD OF A POLYPROPYLENE AND A POLYPROPYLENE OBTAINED THEREFROM (AS Amended) LG CHEM, LTD. (KR) 2016-07-21 US disclosed
EP-3034523-A1 METHOD FOR PREPARING PROPYLENE-1-BUTENE COPOLYMER AND PROPYLENE-1-BUTENE COPOLYMER OBTAINED THEREBY LG Chem, Ltd. (KR) 2016-06-22 EP disclosed
US-9284386-B2 Ansa-metallocene compound and method for preparing supported catalyst using the same LG CHEM, LTD. (KR) 2016-03-15 US disclosed
US-20150073107-A1 ANSA-METALLOCENE COMPOUND AND METHOD FOR PREPARING SUPPORTED CATALYST USING THE SAME LG CHEM, LTD. (KR) 2015-03-12 US disclosed
US-20150031844-A1 NON-SUPPORTED HETEROGENEOUS POLYOLEFIN POLYMERIZATION CATALYST COMPOSITION AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2015-01-29 US disclosed
EP-1115730-B1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORP (US) 2002-10-02 EP disclosed
EP-1115730-A1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORPORATION (US) 2001-07-18 EP disclosed
US-6248832-B1 AMORPHOUS AND CRYSTAL STRUCTURE BLEND EXXON MOBILE CHEMICAL PATENTS INC. 2001-06-19 US disclosed
WO-2000017213-A1 CATALYTIC PROCESS FOR ISOMERIZING METALLOCENES ALBEMARLE CORPORATION (US) 2000-03-30 WO disclosed
US-5965759-A Catalytic process for isomerizing metallocenes ALBEMARLE CORPORATION (US) 1999-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150073107-A1 ANSA-METALLOCENE COMPOUND AND METHOD FOR PREPARING SUPPORTED CATALYST USING THE SAME MNS1, NCL, NUMA1 PDCD1 1239/4885CD274 1161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.