Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TPH1 | P17752 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585899 | 0.85 | PLG (0.43) | PKMF2F10PLGPLAU | |
| Hydrochloric Acid SCHEMBL7584788 | 0.85 | PLG (0.43) | PKMF2F10PLGPLAU | |
| Hydrochloric Acid SCHEMBL7587516 | 0.72 | KMT2A (0.46) | PKMSLC6A4DPP4KMT2ATPH1 | |
| Water SCHEMBL29798071 | 0.67 | SLC7A5 (0.62) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL29375097 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL29401985 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL29584308 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL837890 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL93303 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 | |
| SCHEMBL93304 | 0.66 | SLC7A5 (0.65) | PKMDPP4TPH1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635008-B1 | PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS | PENTAPHARM AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| US-5607937-A | Piperazides of substituted phenylalanine derivatives as thrombin inhibitors | PENTAPHARM AG (CH) | 1997-03-04 | — | — | US | disclosed |